Kidney injury is a relatively common complication of the use of aminoglycosides.
Inflammation and oxidative stress play a key role in gentamicin (GM) nephrotoxicity. We …

Gentamicin (GM) is an antibiotic belonging to an aminoglycoside family that might induce
nephrotoxicity in human and animal models via oxidative stress. Toll-like receptors (TLRs) …

The present study was designed to explore the possible protective effects of agmatine, a
known nitric oxide (NO) synthase inhibitor, against gentamicin-induced nephrotoxicity in …

Gentamicin is an aminoglycoside antibiotic commonly used to treat Gram-negative bacterial
infections that possesses considerable nephrotoxicity. Oxymatrine is a phytochemical with …

Gentamicin is commonly used against gram-negative microorganisms. Its therapeutic use is
mainly limited by nephrotoxicity. This study was aimed at evaluating the effect of rutin on …

Background: Gentamicin (GM) is the commonly used antibiotics against Gram-negative
infection, but the nephrotoxic potential of drug limit its clinical interest. The aim of this study …

Background and aims. Gentamicin (GM) is still considered to be an important antibiotic
against life-threatening, gram-negative bacterial infections despite its known nephrotoxic …

Gentamicin is a commonly used aminoglycoside antibiotic. However, its therapeutic use is
limited by its nephrotoxicity. The mechanisms of gentamicin-induced nephrotoxicity are …

Background: As the use of Gentamicin became more widespread, the drug's harmful effects,
particularly nephrotoxicity, became increasingly well-known. Antibacterial and anti …

Objectives: Nephrotoxicity is a renal-specific situation in which the excretion of toxic
metabolites is reduced due to toxic agents and drugs. Gentamicin is an antibiotic belongs to …