Differential regulation and properties of MAPKs

M Raman, W Chen, MH Cobb - Oncogene, 2007 - nature.com
Mitogen-activated protein kinases (MAPKs) regulate diverse cellular programs including
embryogenesis, proliferation, differentiation and apoptosis based on cues derived from the …

[HTML][HTML] Atypical mitogen-activated protein kinases: structure, regulation and functions

P Coulombe, S Meloche - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
Mitogen-activated protein (MAP) kinases are a family of serine/threonine kinases that play a
central role in transducing extracellular cues into a variety of intracellular responses ranging …

The ERK cascade: a prototype of MAPK signaling

H Rubinfeld, R Seger - Molecular biotechnology, 2005 - Springer
Sequential activation of protein kinases within the mitogen-activated protein kinase (MAPK)
cascades is a common mechanism of signal transduction in many cellular processes. Four …

Mitogen-activated protein kinases in cell-cycle control

RA MacCorkle, TH Tan - Cell biochemistry and biophysics, 2005 - Springer
The mitogen-activated protein kinase (MAPK) family of kinases connects extracellular stimuli
with diverse cellular responses ranging from activation or suppression of gene expression to …

Role of MAPKs in development and differentiation: lessons from knockout mice

M Aouadi, B Binetruy, L Caron, Y Le Marchand-Brustel… - Biochimie, 2006 - Elsevier
The ERK, p38MAPK, JNK mitogen-activated protein kinases (MAPKs) are intracellular
signaling pathways that play a pivotal role in many essential cellular processes such as …

[HTML][HTML] MAP kinase pathways

DK Morrison - Cold Spring Harbor perspectives in …, 2012 - cshperspectives.cshlp.org
MAP Kinase Pathways Cold Spring Harbor Perspectives in Biology Skip to main page content
HOME ABOUT SUBJECT COLLECTIONS ARCHIVE SUBSCRIBE ADVERTISE ALERTS …

The mitogen-activated protein kinases, ERK1 and ERK2.

MH Cobb, JE Hepler, M Cheng… - Seminars in cancer …, 1994 - europepmc.org
The MAP kinases are ubiquitous enzymes that are activated in a complex fashion and
inactivated by multiple phosphatases including a dedicated dual specificity enzyme. These …

[HTML][HTML] Alternative splicing of MAPKs in the regulation of signaling specificity

G Maik-Rachline, I Wortzel, R Seger - Cells, 2021 - mdpi.com
The mitogen-activated protein kinase (MAPK) cascades transmit signals from extracellular
stimuli to a variety of distinct cellular processes. The MAPKKs in each cascade specifically …

[HTML][HTML] MAP kinase pathways

MH Cobb - Progress in biophysics and molecular biology, 1999 - Elsevier
MAP kinases help to mediate diverse processes ranging from transcription of
protooncogenes to programmed cell death. More than a dozen mammalian MAP kinase …

[HTML][HTML] Signaling by the germinal center kinase family of protein kinases

JM Kyriakis - Journal of Biological Chemistry, 1999 - ASBMB
Mammalian mitogen-activated protein kinase (MAPK) 1 pathways regulate an extensive
range of cellular processes including gene transcription, cytoskeletal organization …