Gap junctions are common features in the vasculature, long thought to provide a pathway for
cell-cell signaling. Emerging understanding of the gap-junctional proteins (connexins) and …

Endothelial dysfunction underlies the pathogenesis of preeclampsia, but its mechanism has
not yet been completely understood. Elevated oxygen free radicals may partially explain the …

Pre-eclampsia (PE) is a leading cause of maternal hypertension in pregnancy and is
associated with fetal growth restriction, premature birth, and fetal and maternal mortality …

Preeclampsia is a life-threatening vascular disorder of pregnancy due to a failing stressed
placenta. Millions of women risk death to give birth each year and globally each year, almost …

Introduction 3. Pathogenesis 3.1. Abnormal development of the placenta 3.2. Remodeling of
the spiral arteries 3.3. Hypoperfusion, hypoxia, and ischemia of the placenta 3.4. Systemic …

Preeclampsia is a serious, pregnancy-specific, multi-organ disease process of compound
aetiology. It affects 3–6% of expecting mothers worldwide and it persists as a leading cause …

Preeclampsia, a hypertensive disease of pregnancy of unknown etiology, is intensely
studied as a model of cardiovascular disease (CVD) not only due to multiple shared …

Background During normal pregnancy, placental oxidative stress (OS) is present during all
three trimesters and is necessary to obtain normal cell function. However, if OS reaches a …

Preeclampsia (PE) is an often fatal pathology characterized by hypertension and proteinuria
at the 20th week of gestation that affects 5–10% of the pregnancies. The problem is …

Abstract Purpose of Review To review and summarize what is known about cerebrovascular
derangements during preeclampsia. Recent Findings Preeclampsia is a devastating …