CELLS MEDIATING SPECIFIC IN VITRO CYTOTOXICITY: II. PROBABLE AUTONOMY OF THYMUS-PROCESSED LYMPHOCYTES (TCELLS) FOR THE KILLING OF ALLOGENEIC T …

P Golstein, H Wigzell, H Blomgren… - The Journal of …, 1972 - rupress.org
In order to investigate whether only T cells are involved in a cell-mediated cytotoxic system
in vitro, we tested the cytotoxicity of immune killing cell populations as deprived as possible …

Cytotoxic lymphocytes as effector cells of cell-mediated immunity

KT Brunner, JC Cerottini - Progress in immunology, 1971 - Elsevier
Publisher Summary This chapter discusses about cytotoxic lymphocytes as effector cells of
cell-mediated immunity. Allograft and tumor immunity are considered to be manifestations of …

Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype …

H Shiku, P Kisielow, MA Bean, T Takahashi… - The Journal of …, 1975 - rupress.org
The cell-mediated cytotoxicity (CMC) of nonadherent cells from the peritoneal cavity (NAPC)
of alloimmunized mice can be measured by the [3H] proline microassay. The exhibition of …

GENERATION OF CYTOTOXIC LYMPHOCYTES IN MIXED LYMPHOCYTE REACTIONS: I. SPECIFICITY OF THE EFFECTOR CELLS

J Forman, G Möller - The Journal of Experimental Medicine, 1973 - rupress.org
Generation of cytotoxic effector cells by a unidirectional mixed lymphocyte reaction (MLR) in
the mouse H-2 system was studied using labeled YAC (H-2a) leukemia cells as targets. The …

Further evidence for autonomy of T cells mediating specific in vitro cytotoxicity: efficiency of very small amounts of highly purified T cells

P Golstein, H Blomgren - Cellular Immunology, 1973 - Elsevier
Cytotoxic educated thymus cells were either incubated in a plastic flask or in the presence of
iron with subsequent magnetic removal of iron-containing cells or subjected to a …

Generation of cytotoxic T lymphocytes in vitro: I. Response of normal and immune mouse spleen cells in mixed leukocyte cultures

JC Cerottini, HD Engers, HR MacDonald… - The Journal of …, 1974 - rupress.org
Mouse cytotoxic T lymphocytes (CTL) were generated in mixed leukocyte cultures (MLC)
using spleen cells as responding cells and irradiated allogeneic spleen cells as stimulating …

Generation of cytotoxic T lymphocytes in vitro: V. Response of normal and immune spleen cells to subcellular alloantigens

HD Engers, K Thomas, JC Cerottini… - The Journal of …, 1975 - journals.aai.org
Subcellular particulate membrane fragments prepared from murine lymphoid or tumor cells
were used as a cell-free antigen source in order to stimulate the generation of cytolytic …

CELLS MEDIATING SPECIFIC IN VITRO CYTOTOXICITY: I. DETECTION OF RECEPTOR-BEARING LYMPHOCYTES

P Golstein, EAJ Svedmyr, H Wigzell - The Journal of Experimental …, 1971 - rupress.org
Spleen cells from mice immunized with allogeneic tumor cells are incubated on different
fibroblast monolayers. The nonadsorbed cells are tested for cytotoxicity against 51Cr …

Thymocytes from mice immunized against an allograft render bone-marrow cells specifically cytotoxic

CK Grant, GA Currie, P Alexander - The Journal of Experimental …, 1972 - rupress.org
Thymocytes from C57BL mice immunized with the DBA/2 lymphoma L5178Y exert in vitro an
immunologically specific cytotoxic action against the target cells in the presence of bone …

Isolation and characterization of individual functionally reactive cytotoxic T lymphocytes: conjugation, killing and recycling at the single cell level

D Zagury, J Bernard, N Thierness… - European Journal of …, 1975 - Wiley Online Library
Isolation and characterization of individual functionally reactive cytotoxic T lymphocytes
have been achieved. Peritoneal exudate cytotoxic lymphocytes were obtained from BALB/c …