Molecular basis of Hurthle cell papillary thyroid carcinoma

CC Cheung, S Ezzat, L Ramyar… - The Journal of …, 2000 - academic.oup.com
Among thyroid neoplasms, Hurthle cell tumors (HCTs) have traditionally been a distinct
diagnostic category. Hurthle cell adenomas are encapsulated follicular lesions with benign …

Molecular analysis of Hurthle cell neoplasms by gene profiling

DJ Finley, B Zhu, TJ Fahey III - Surgery, 2004 - Elsevier
BACKGROUND: Though Hurthle cell tumors are considered a variant of follicular lesions,
recent data have suggested that Hurthle cell carcinomas may be more closely related to …

Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy

I Ganly, J Ricarte Filho, S Eng… - The Journal of …, 2013 - academic.oup.com
Context: Hurthle cell cancer (HCC) is an understudied cancer with poor prognosis.
Objective: Our objective was to elucidate the genomic foundations of HCC. Design and …

[HTML][HTML] Pathologic features, proliferative activity, and cyclin D1 expression in Hurthle cell neoplasms of the thyroid

LA Erickson, L Jin, JR Goellner, C Lohse, VS Pankratz… - Modern Pathology, 2000 - Elsevier
Making a histologic distinction between Hurthle cell adenomas and carcinomas sometimes
may be difficult. We analyzed a series of Hurthle cell lesions to determine whether specific …

The RET/PTC Oncogene Is Frequently Activated in Oncocytic Thyroid Tumors (Hurthle Cell Adenomas and Carcinomas), but Not in Oncocytic Hyperplastic Lesions

G Chiappetta, P Toti, F Cetta, A Giuliano… - The Journal of …, 2002 - academic.oup.com
Hurthle cell adenomas and carcinomas, characterized by the presence of oncocytic cells,
are unusual thyroid neoplasms, the treatment of which is still controversial. We analyzed …

Hürthle cell tumors: using molecular techniques to define a novel classification system

G Belchetz, CC Cheung, J Freeman… - … –Head & Neck …, 2002 - jamanetwork.com
Background Sinceret/PTCgene rearrangements are specific to papillary thyroid carcinoma
(PTC), the diagnosis of Hürthle cell PTC (HCPTC) has recently been expanded to include a …

Pathologic study and clinical significance of Hürthle cell papillary thyroid carcinoma

KT Mai, J Thomas, HM Yazdi… - Applied …, 2004 - journals.lww.com
Hürthle cell papillary thyroid carcinoma is a variant of papillary thyroid carcinoma (PTC). Its
pathologic and clinical significance has not been well documented. The authors studied the …

Hurthle cell carcinoma: a population‐level analysis of 3311 patients

P Goffredo, SA Roman, JA Sosa - Cancer, 2013 - Wiley Online Library
BACKGROUND: Hurthle cell carcinoma (HCC) is an uncommon and more aggressive
thyroid cancer. To date, there is a paucity of data at a population level. In this study …

[HTML][HTML] Hurthle cell tumours of the thyroid. Personal experience and review of the literature

A Barnabei, E Ferretti, R Baldelli… - Acta …, 2009 - ncbi.nlm.nih.gov
Hurthle cell carcinoma represents about 5% of differentiated thyroid carcinomas. The
prognosis of the malignant type of the tumour is still under debate as some Authors have …

RET rearrangements in archival oxyphilic thyroid tumors: new insights in tumorigenesis and classification of Hürthle cell carcinomas?

PB Musholt, F Imkamp, R Von Wasielewski… - Surgery, 2003 - Elsevier
BACKGROUND: Oncocytic carcinomas (Hürthle cell carcinomas [HCCs]) are commonly
considered a subgroup of follicular thyroid carcinomas (FTCs). Recent characterization of a …