Sarcoplasmic hypertrophy in skeletal muscle: a scientific “unicorn” or resistance training adaptation?

MD Roberts, CT Haun, CG Vann, SC Osburn… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fibers are multinucleated cells that contain mostly myofibrils suspended in
an aqueous media termed the sarcoplasm. Select evidence suggests sarcoplasmic …

A critical evaluation of the biological construct skeletal muscle hypertrophy: size matters but so does the measurement

CT Haun, CG Vann, BM Roberts, AD Vigotsky… - Frontiers in …, 2019 - frontiersin.org
Skeletal muscle is highly adaptable and has consistently been shown to morphologically
respond to exercise training. Skeletal muscle growth during periods of resistance training …

Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy

CT Haun, CG Vann, SC Osburn, PW Mumford… - PloS one, 2019 - journals.plos.org
Cellular adaptations that occur during skeletal muscle hypertrophy in response to high-
volume resistance training are not well-characterized. Therefore, we sought to explore how …

Hypertrophy and hyperplasia

JD Macdougall - Strength and power in sport, 2003 - Wiley Online Library
Skeletal muscle is an extremely dynamic tissue with a remarkable capacity for adapting,
both structurally and physiologically, to different forms of functional overload. A functional …

Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis

JK Petrella, J Kim, DL Mayhew… - Journal of applied …, 2008 - journals.physiology.org
A present debate in muscle biology is whether myonuclear addition is required during
skeletal muscle hypertrophy. We utilized K-means cluster analysis to classify 66 humans …

The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis

F Damas, CA Libardi, C Ugrinowitsch - European journal of applied …, 2018 - Springer
Resistance training (RT)-induced skeletal muscle hypertrophy is a highly intricate process.
Despite substantial advances, we are far from understanding exactly how muscle …

Molecular regulation of exercise-induced muscle fiber hypertrophy

MM Bamman, BM Roberts… - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Skeletal muscle hypertrophy is a widely sought exercise adaptation to counteract the muscle
atrophy of aging and disease, or to improve athletic performance. While this desired muscle …

Growing muscle has different sarcolemmal properties from adult muscle: a proposal with scientific and clinical implications: reasons to reassess skeletal muscle …

MD Grounds, T Shavlakadze - Bioessays, 2011 - Wiley Online Library
We hypothesise that the sarcolemma of an actively growing myofibre has different properties
to the sarcolemma of a mature adult myofibre. Such fundamentally different properties have …

Analysis of skeletal muscle hypertrophy in models of increased loading

SC Bodine, K Baar - Myogenesis: methods and protocols, 2012 - Springer
Skeletal muscle is a highly adaptive tissue that modifies its size in response to a variety of
external stimuli. In adult mammals, skeletal muscle hypertrophy occurs primarily as a …

Physiological differences between low versus high skeletal muscle hypertrophic responders to resistance exercise training: current perspectives and future research …

MD Roberts, CT Haun, CB Mobley… - Frontiers in …, 2018 - frontiersin.org
Numerous reports suggest there are low and high skeletal muscle hypertrophic responders
following weeks to months of structured resistance exercise training (referred to as low and …