A Randomized Phase II Trial of Flutamide vs Chlormadinone Acetate in Previously Untreated Advanced Prostatic Cancer

H Akaza, M Usami, T Kotake, K Koiso… - Japanese Journal of …, 1993 - academic.oup.com
We have conducted a double-blind comparative study of flutamide and chlormadinone
acetate (CMA) on patients with stage C or D prostatic cancer and with no prior experience of …

A rationale for the use of non‐steroidal anti‐androgens in the management of prostate cancer

RC Benson - The Prostate, 1992 - Wiley Online Library
Flutamide is a non‐steroidal anti‐androgen which has been used to treat prostate cancer.
Results to date indicate that flutamide is as effective as other conventional therapy. It has …

Effects of flutamide as a second‐line agent for maximum androgen blockade of hormone refractory prostate cancer

K Nishimura, N Arichi, S Tokugawa… - … journal of urology, 2007 - Wiley Online Library
We analyzed clinical effects of flutamide as a second‐line agent for maximum androgen
blockade (MAB) in patients with relapsing prostate cancer who received bicalutamide as the …

Long-term experience with flutamide in patients with prostatic carcinoma

GR Prout Jr, MA Keating, PP Griffin, SF Schiff - Urology, 1989 - Elsevier
Fifty-two patients with previously untreated metastatic carcinoma of the prostate were treated
with flutamide 250 mg tid. Response was classified according to objective and subjective …

Flutamide versus orchidectomy in the treatment of metastatic prostate carcinoma

L Boccon-Gibod, G Fournier, P Bottet, JM Marechal… - European …, 1997 - karger.com
Purpose: To compare in a randomized clinical trial the therapeutic efficacy of the
nonsteroidal antiandrogen flutamide 250 mg tid to testicular androgen suppression by …

Flutamide as primary treatment for metastatic prostatic cancer

R Lundgren - British journal of urology, 1987 - Wiley Online Library
Ten men with newly diagnosed generalised cancer of the prostate were treated with
Flutamide (SCH 13521). After 18 months of treatment, one patient had stable disease and …

Cost‐effective models for flutamide for prostate carcinoma patients: Are they helpful to policy makers?

CL Bennett, D Matchar, D McCrory… - … Journal of the …, 1996 - Wiley Online Library
BACKGROUND More than 50,000 male patients received hormonal therapy for metastatic
prostate carcinoma in 1995. Nonsteroidal antiandrogens, such as flutamide, when used in …

Flutamide as an alternative anti-androgen agent and predictor of the efficacy of novel androgen receptor-targeted agents

N Yamaguchi, S Morizane, T Yumioka… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: There are few reports that verify the relationship between the therapeutic
effects of flutamide and novel androgen receptor-targeted agents. We aimed to evaluate the …

Flutamide versus prednisone in patients with prostate cancer symptomatically progressing after androgen-ablative therapy: a phase III study of the European …

SD Fossa, PHT Slee, M Brausi, S Horenblas… - Journal of clinical …, 2001 - ascopubs.org
PURPOSE: Time to progression (TTP), overall survival, and quality of life (QL) were
compared in patients with hormone-resistant prostate cancer (HRPC) treated with …

The antiandrogen withdrawal syndrome. Experience in a large cohort of unselected patients with advanced prostate cancer

EJ Small, S Srinivas - Cancer, 1995 - Wiley Online Library
Background. Flutamide withdrawal has been reported to be therapeutically efficacious for
patients with hormone‐refractory prostate cancer, with a reported prostate specific antigen …