Establishment of an IL‐2 independent, human T‐cell line possessing only the p70 IL‐2 receptor
G Starkebaum, TP Loughran JR… - … journal of cancer, 1991 - Wiley Online Library
A continuous cell line was established from the blood of a patient (HH) with an aggressive
cutaneous T‐cell leukemia/lymphoma who lacked antibodies to human T lymphotrophic …
cutaneous T‐cell leukemia/lymphoma who lacked antibodies to human T lymphotrophic …
Analysis of IL-2, IL-4 and their receptors in clonally-related cell lines derived from a patient with a progressive cutaneous T-cell lymphoproliferative disorder
MA Wasik, DC Seldin, JR Butmarc, R Gertz… - Leukemia & …, 1996 - Taylor & Francis
Three clonally related T-cell lymphoma lines (PB-1, 2A, and 2B) were examined for
expression of IL-2, IL-4, and their receptors. All three lines were derived from a single patient …
expression of IL-2, IL-4, and their receptors. All three lines were derived from a single patient …
[引用][C] IL‐2 receptor dysfunction and adult T‐cell leukemia
J Yodoi, T Uchiyama - Immunological Reviews, 1986 - Wiley Online Library
Our knowledge of the mechanism of lymphocyte activation and proliferation by interleukin-2
(IL-2) and interleukin-2 receptor (IL-2-R) has expanded rapidly since the cloning of the …
(IL-2) and interleukin-2 receptor (IL-2-R) has expanded rapidly since the cloning of the …
Murine spontaneous T‐cell leukemia constitutively expressing IL‐2 receptor—a model for human T‐cell malignancies expressing IL‐2 receptor
H Lugasi, S Hajos, JR Murphy, TB Strom… - … journal of cancer, 1990 - Wiley Online Library
We describe a new, spontaneously occurring BALB/c‐derived murine T‐cell leukemia. The
leukemic cells, designated LB, grow rapidly and progressively in the syngeneic host with no …
leukemic cells, designated LB, grow rapidly and progressively in the syngeneic host with no …
Differential effects on expression of IL‐2 receptors (p55 and p70) by the HTLV‐I pX DNA
Abnormal expression of the low‐affinity receptor for inter‐leukin‐2 (IL‐2R) is a characteristic
of the HTLV‐I (+) leukemic T cells in adult T‐cell leukemia (ATL). Despite the expression of …
of the HTLV‐I (+) leukemic T cells in adult T‐cell leukemia (ATL). Despite the expression of …
Synergistic and antagonistic effects of IL-1 alpha and IL-4, respectively, on the IL-2-dependent growth of a T cell receptor-gamma delta+ human T leukemia cell line.
D Santoli, R O'Connor, A Cesano, P Phillips… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
Abstract The TALL-103/2 cell line was derived from an immature acute T lymphocytic
leukemia with T-myeloid differentiating capacity. The leukemic cells were first expanded in …
leukemia with T-myeloid differentiating capacity. The leukemic cells were first expanded in …
IL-2-dependent proliferation of murine T cells requires expression of both the p55 and p70 subunits of the IL-2 receptor.
DL Jankovic, A Rebollo, A Kumar, M Gibert… - Journal of immunology …, 1990 - journals.aai.org
An IL-4-dependent T cell clone (LD8) was isolated from the murine IL-2-dependent cytotoxic
T cell line C30. 1. This clone has lost the capacity to proliferate in response to IL-2 after long …
T cell line C30. 1. This clone has lost the capacity to proliferate in response to IL-2 after long …
Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia …
T Hori, T Uchiyama, M Tsudo, H Umadome, H Ohno… - 1987 - ashpublications.org
We established an interleukin 2 (IL-2)-dependent human T cell line, Kit 225, from a patient
with T cell chronic lymphocytic leukemia (T-CLL) with OKT3+,-T4+,-T8-phenotype. Southern …
with T cell chronic lymphocytic leukemia (T-CLL) with OKT3+,-T4+,-T8-phenotype. Southern …
Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling.
N Arima, M Kamio, K Imada, T Hori, T Hattori… - The Journal of …, 1992 - rupress.org
Functional studies of the interleukin 2 receptor (IL-2R) of two (ED515-D and Kit225) IL-2-
dependent and three (ED515-I, 3T3-alpha beta 11, and Hut102) IL-2-independent cell lines …
dependent and three (ED515-I, 3T3-alpha beta 11, and Hut102) IL-2-independent cell lines …
Expression of interleukin 2 receptors on human carcinoma cell lines and tumor growth inhibition by interleukin 2
S Yasumura, WC Lin, E Weidmann… - … journal of cancer, 1994 - Wiley Online Library
We have previously shown that human squamous cell carcinomas (SCC) express the
interleukin 2 receptor (IL2R)‐α and‐β chains, and that the ligand, IL2, directly inhibits growth …
interleukin 2 receptor (IL2R)‐α and‐β chains, and that the ligand, IL2, directly inhibits growth …