Abstract Interleukin 2 receptors (IL-2-R) are composed of (at least) two chains: the α chain
(or p55 or Tac) and the β chain (or p70 or p75). The association of both chains constitutes …

The binding of IL-2 to its specific receptor (IL-2R) triggers various cellular events including
the induction of nuclear proto-oncogenes (c-fos, c-jun and c-myc genes) and the …

Several human head and neck squamous carcinoma cell lines were found to bind 125I-
labeled or fluorescein-labeled interleukin 2 (IL-2). This binding was inhibited by an excess of …

The establishment of an in vitro model for cutaneous T cell lymphomas and Sézary
syndrome has been difficult since T cells from individuals with these diseases do not …

Adult T-cell leukemia (ATL) cells have been shown to express the receptor for IL-2 by
studies using anti-CD25 monoclonal antibody, but these cells usually show no or only a …

It has been previously demonstrated that human carcinomas express interleukin‐2 receptor
(IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for …

The expression of the interleukin-4 receptor on human blood and tonsil lymphocytes has
been studied using a monoclonal antibody and high-sensitivity immunofluorescence flow …

Late-phase human T-cell lymphotropic virus I-associated adult T-cell leukemia cells express
IL-2 receptors (IL-2R) but no longer produce IL-2. We have reported that the IL-2 …

Abstract Interleukin-2 (IL-2) is recognized as a T cell growth factor. We have previously
reported that human carcinoma cell lines are inhibited in growth by exogenous IL-2, which …

The high-affinity interleukin 2 (IL-2) receptor is a heterotrimer consisting of α, β, and γ
subunits. We examined the concentration of subunit mRNA for each of the three protein …