Oncogenic effects of overexpression of the interleukin-3 receptor on hematopoietic cells.

LS Steelman, PA Algate, WL Blalock, XY Wang… - Leukemia, 1996 - europepmc.org
To elucidate the relationship between malignant transformation and cytokine receptor
expression, the interleukin-3 receptor (IL-3R) complex was examined in an IL-3-dependent …

Identification of a distinct low-affinity receptor for human interleukin-4 on pre-B cells

WC Fanslow, MK Spriggs, CT Rauch, KN Clifford… - 1993 - ashpublications.org
Abstract Biotinylated interleukin-4 (IL-4) was used to examine IL-4 receptor (IL-4R)
expression on a range of human B-cell lines by flow cytometry. Using high concentrations of …

Characterization of a monoclonal rat anti-mouse interleukin 2 (IL-2) receptor antibody and its use in the biochemical characterization of the murine IL-2 receptor

GN Gaulton, J Bangs, S Maddock, T Springer… - Clinical immunology and …, 1985 - Elsevier
Anti-murine interleukin 2 (IL-2) receptor monoclonal antibodies (mAb) were made from rats
immunized with murine cytotoxic lymphocytes. One mAb, designated M7/20, strongly …

Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells.

PL Kilian, KL Kaffka, AS Stern, D Woehle… - … (Baltimore, Md.: 1950 …, 1986 - journals.aai.org
Pure, E. coli-derived recombinant murine interleukin 1 alpha (IL 1 alpha) was labeled with
125I and used for receptor binding studies. The 125I-IL 1 binds to murine EL-4 thymoma …

IL‐2‐and IL‐2‐R‐independent proliferation of T‐cell lines from adult T‐cell leukemia/lymphoma patients

T Katoh, T Harada, S Morkawa… - International journal of …, 1986 - Wiley Online Library
Human T‐cell leukemia/lymphoma virus 1 (HTLV‐1) is known to be associated with adult T‐
cell leukemia/lymphoma (ATL) as an etiological agent. The mechanism of leukemogenesis …

Receptors for Interleukin (IL)-4 Do Not Associate with the Common γChain, and IL-4 Induces the Phosphorylation of JAK2 Tyrosine Kinase in Human Colon …

T Murata, PD Noguchi, RK Puri - Journal of Biological Chemistry, 1995 - ASBMB
We have previously reported on the expression of interleukin-4 receptors (IL-4R) on many
human epithelial cancer cells; however, the binding characteristics, structure, function, and …

Expression of high-affinity IL-4 receptors on human melanoma, ovarian and breast carcinoma cells

NI Obiri, JP Siegel, F Varricchio… - Clinical & Experimental …, 1994 - academic.oup.com
It has previously been shown that murine sarcoma cells express high-affinity IL-4 receptors
(1L-4R) which are internalized after binding to the ligand (Puri et al., Cancer Res 1991; 51 …

Transcript synthesis and surface expression of the interleukin-2 receptor (alpha-, beta-, and gamma-chain) by normal and malignant myeloid cells

RR Schumann, T Nakarai, HJ Gruss, MA Brach… - 1996 - ashpublications.org
Expression of the interleukin-2 receptor alpha-(IL-2Ralpha-), IL-2Rbeta-, and the recently
identified IL-2Rgamma-chain was examined on a wide range of cells of myeloid origin …

The IL-2/IL-2 Receptor System: Involvement of a Novel Receptor Subunit, γ Chain, in Growth Signal Transduction

K SUGAMURA, T TAKESHITA, H ASAO… - The Tohoku journal of …, 1992 - jstage.jst.go.jp
SUGAMURA, K., TAKESHITA, T., ASAO, H., KUMAKI, S., OHBO, K., OHTANI, K. and
NAKAMURA, M. The IL-2/IL-2 Receptor System: Involvement of a Novel Receptor Subunit, y …

Two high-affinity interleukin 1 receptors represent separate gene products.

R Chizzonite, T Truitt, PL Kilian… - Proceedings of the …, 1989 - National Acad Sciences
Interleukin 1 (IL-1) is a polypeptide hormone that mediates a broad range of biological
activities and interacts with surface receptors on numerous cell types. Equilibrium binding …