Expression of the interleukin-2 receptor alpha-(IL-2Ralpha-), IL-2Rbeta-, and the recently
identified IL-2Rgamma-chain was examined on a wide range of cells of myeloid origin …

In addition to the regulation of B lymphocyte growth and differentiation, the cytokine IL-4
(BSF-1) exerts effects on T lymphocytes and other bone marrow-derived lineages. We show …

Human monocytes express functional IL-2 receptors (IL-2R) and are directly activated by IL-
2 to exert effector and secretory functions. In this study, we show that IL-4 selectively …

The interleukin 2 receptor (IL-2R) is composed of at least three different chains that may be
variably expressed on normal and neoplastic lymphocytes. While considerable knowledge …

The functional, high-affinity interleukin 2 receptor (IL-2R) consists of at least two receptor
components, IL-2R alpha (p55) and IL-2R beta (p70-75). The cDNA encoding the murine IL …

Abstract Interleukin (IL)‐1‐like protein 1 (IL‐1L1) is a 155‐amino acid protein that shares
27% identity with IL‐1β and 47% with IL‐1 receptor antagonist (IL‐1ra). A 2.7‐kb IL‐1L1 …

Abstract Interleukin-2 (IL-2) in combination with the IL-2 receptor has an essential role in
antigen-stimulated proliferation of T lymphocytes1–3. It has been proposed that the …

Cell surface expression of the high affinity IL-2R regulates, in part, the proliferative response
occurring in Ag-or mitogen-activated T cells. The functional high affinity IL-2R is composed …

The discovery and molecular characterization of interleukin-2 (IL-2) has had a considerable
impact on basic and clinical immunology (Morgan et al., 1976; Taniguchi et al., 1963; …

Interleukin 2 (IL–2) mediated signalling results from ligand binding and subsequent hetero-
dimerization of IL–2rβ and γc. The high-affinity IL–2 receptor (IL–2r) is a heterotrimer …