Frozen sections of 52 human solid tumours (38 malignant and 14 benign) of varied
histogenesis were immunohistochemically stained with well characterised monoclonal …

High concentrations of interleukin 2 (IL 2) were shown to produce a delayed but pronounced
proliferation of purified resting T cells in the apparent absence of other activation signals …

During the growth of interleukin 2 (IL-2)-dependent T cells IL-2 binding is followed by
internalization of the complex between IL-2 and the high affinity IL-2 receptor (HA-IL-2R) …

The expression of the interleukin 4 (IL-4) receptor (IL-4R) and effects of human recombinant
IL-4 on human gastric carcinoma cell lines were studied. We demonstrated that IL-4 …

IL-4 is a cytokine which can induce B-lymphocyte proliferation, increase cell-surface Ia
expression, and induce some activated B cells to differentiate and begin to secrete IgE. IL-4 …

The accessory function for T cell activation and the production of interleukin 1 (IL 1) of adult
T cell leukemia (ATL) cell lines were studied in vitro. ATL cell lines such as Hut-102, MT-1 …

A new rat monoclonal antibody (5A2) directed against the mouse interleukin 2 receptor
(IL2R) is described. This antibody binds specifically to IL2R+ cells, competes with both cold …

The nature of Hodgkin and Reed-Sternberg (H–RS) cells and their normal counterpart
remains a matter of controversy. Our recent investigations have suggested that H–RS-cells …

Lymphocytes from the human (h) IL-2R alpha chain transgenic mice (TGM) constitutively
express high affinity binding sites for hIL-2, consisting of transgenic h-IL-2R alpha and …

T cell-replacing factor (TRF)/IL-5 is a glycosylated polypeptide that acts as a key factor for B
cell growth and differentiation. Since IL-5 action is probably mediated by specific cell surface …