[HTML][HTML] A receptor binding domain of mouse interleukin-4 defined by a solid-phase binding assay and in vitro mutagenesis.
BW Morrison, P Leder - Journal of Biological Chemistry, 1992 - Elsevier
Interleukin 4 (IL-4) is a potent, pleiotropic lymphokine that affects a variety of cells, especially
those of hematopoietic origin. Although murine and human IL-4 are homologous proteins …
those of hematopoietic origin. Although murine and human IL-4 are homologous proteins …
Utilization of the beta and gamma chains of the IL‐2 receptor by the novel cytokine IL‐15.
JG Giri, M Ahdieh, J Eisenman, K Shanebeck… - The EMBO …, 1994 - embopress.org
We have recently cloned a novel cytokine, IL‐15, with shared bioactivities but no sequence
homology with IL‐2. We found high affinity IL‐15 binding to many cell types, including cells …
homology with IL‐2. We found high affinity IL‐15 binding to many cell types, including cells …
Interleukin 2 (IL 2) up-regulates its own receptor on a subset of human unprimed peripheral blood lymphocytes and triggers their proliferation.
A Harel-Bellan, J Bertoglio, A Quillet… - … (Baltimore, Md.: 1950 …, 1986 - journals.aai.org
Several reports indicate that human peripheral blood lymphocytes (PBL) seeded in culture
with purified or recombinant interleukin 2 (IL 2) immediately after separation from the blood …
with purified or recombinant interleukin 2 (IL 2) immediately after separation from the blood …
Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4.
NI Obiri, GG Hillman, GP Haas, S Sud… - The Journal of clinical …, 1993 - Am Soc Clin Investig
Previously, Puri et al.(Puri, RK, M. Ogata, P. Leland, GM Feldman, D. Fitzgerald, and I.
Pastan. 1991. Cancer Res. 51: 3011-3017) have demonstrated that murine sarcoma and …
Pastan. 1991. Cancer Res. 51: 3011-3017) have demonstrated that murine sarcoma and …
A soluble'anchorminus 'interleukin 2 receptor suppresses in vitro interleukin 2-mediated immune responses
N Kondo, S Kondo, A Shimizu, T Honjo, J Hamuro - Immunology letters, 1988 - Elsevier
The immunosuppressive effects of a recombinant soluble IL-2 receptor L chain (s-IL-2R)
were analyzed. S-IL-2R protein was obtained from the conditioned medium of L cells …
were analyzed. S-IL-2R protein was obtained from the conditioned medium of L cells …
[HTML][HTML] Purification of a 130-kDa T cell glycoprotein that binds human interleukin 4 with high affinity.
JP Galizzi, B Castle, O Djossou, N Harada… - Journal of Biological …, 1990 - Elsevier
The interleukin 4 (IL-4) receptor was purified from the gibbon T cell line MLA 144. These
cells were found to express high numbers of human IL-4-binding proteins (5000-6000 …
cells were found to express high numbers of human IL-4-binding proteins (5000-6000 …
Interleukin 1 gene expression in adult T cell leukemia.
Y Wano, T Hattori, M Matsuoka… - The Journal of …, 1987 - Am Soc Clin Investig
The adult T cell leukemia (ATL) is a T cell neoplasm etiologically associated with human T
lymphotropic virus type I (HTLV-I) infection. ATL cells often abnormally express interleukin 2 …
lymphotropic virus type I (HTLV-I) infection. ATL cells often abnormally express interleukin 2 …
Molecular cloning and expression of the murine interleukin‐5 receptor.
S Takaki, A Tominaga, Y Hitoshi, S Mita… - The EMBO …, 1990 - embopress.org
Murine interleukin‐5 (IL‐5) is known to play an essential role in Ig production of B cells and
proliferation and differentiation of eosinophils. Here, we have isolated cDNA clones …
proliferation and differentiation of eosinophils. Here, we have isolated cDNA clones …
Expression of the p70 chain of the IL‐2 receptor on human lymphoid cells: Analysis using a monoclonal antibody and high‐sensitivity immunofluorescence
H Zola, RJ Purling, LY Koh… - Immunology and cell …, 1990 - Wiley Online Library
Using monoclonal antibody (MoAb) against the p70 (β) chain of the interleukin‐2 receptor
(IL‐2R) and a high‐sensitivity immunofluorescence procedure, p70 can be demonstrated on …
(IL‐2R) and a high‐sensitivity immunofluorescence procedure, p70 can be demonstrated on …
The IL-4 receptor: biochemical characterization of IL-4-binding molecules in a T cell line expressing large numbers of receptors.
AD Keegan, MP Beckmann, LS Park… - Journal of immunology …, 1991 - journals.aai.org
Cross-linking of 125I-IL-4 to the surface of cells expressing IL-4R yields as the major IL-4-
binding molecules, polypeptide chains with inferred mw of approximately 70,000 (p70) and …
binding molecules, polypeptide chains with inferred mw of approximately 70,000 (p70) and …