Searching for the holy grail of a staphylococcal vaccine

I Thomsen, H Dudney, CB Creech - Human Vaccines, 2010 - Taylor & Francis
The pursuit of an effective staphylococcal vaccine has never been more critical, as
community-associated MRSA has become the most common bacterial infection in the US. In …

Will we ever see the approval of a Staphylococcus aureus vaccine?

JM Patti - Expert review of anti-infective therapy, 2011 - Taylor & Francis
Staphylococcus aureus infections, particularly those that are methicillin-resistant (MRSA),
continue to plague patients and clinicians alike. The prevalence of MRSA is a global …

Progress Toward a Staphylococcus aureus Vaccine

RS Daum, B Spellberg - Clinical Infectious Diseases, 2012 - academic.oup.com
High attack rates and the ability of Staphylococcus aureus to develop resistance to all
antibiotics in medical practice heightens the urgency for vaccine development. S. aureus …

Will there ever be a universal Staphylococcus aureus vaccine?

GB Pier - Human vaccines & immunotherapeutics, 2013 - Taylor & Francis
Developing a universal vaccine for S. aureus is a top priority but to date we have only had
failures in human clinical trials. Given the plethora of bacterial virulence factors, broad range …

Immunotherapies for Staphylococcus aureus: current challenges and future prospects

S Deresinski, V Herrera - Infection Control & Hospital Epidemiology, 2010 - cambridge.org
Development of an effective vaccine against Staphylococcus aureus would provide great
potential public health benefit. We present a brief overview of the current knowledge in this …

[PDF][PDF] Recent developments for Staphylococcus aureus vaccines: clinical and basic science challenges

RA Proctor - Eur Cell Mater, 2015 - ecmjournal.org
Bacterial vaccines have made dramatic impacts upon morbidity and mortality caused by a
number of common pathogens, but a vaccine to prevent Staphylococcus aureus infections …

Development of a Staphylococcus aureus Vaccine: An Ongoing Journey

RA Proctor - Clinical Infectious Diseases, 2023 - academic.oup.com
Vaccine Efficacy (STRIVE) trial is another disappointment. However, the information
provided by Hassanzadeh et al is extremely valuable as it can instruct future clinical trials …

Updates on Staphylococcal Vaccines

A Scafa-Udriste, MI Popa, GL Popa - Microbiology Research, 2023 - mdpi.com
Staphylococcus aureus, a prevalent human pathogen and a leading cause of hospital-
acquired infections, is increasingly evolving antibiotic-resistant strains, increasing mortality …

Where does a Staphylococcus aureus vaccine stand?

VG Fowler Jr, RA Proctor - Clinical Microbiology and Infection, 2014 - Wiley Online Library
In this review, we examine the current status of S taphylococcus aureus vaccine
development and the prospects for future vaccines. Examination of the clinical trials to date …

Staphylococcus aureus: current state of prevalence, impact, and vaccine development

M Brett, SB Bradfute - Current pharmaceutical design, 2015 - ingentaconnect.com
Staphylococcus aureus is a fastidious pathogen of global concern. S. aureus can not only
cause a wide range of serious infections, but can also colonize healthy individuals …