Impact of metastatic estrogen receptor and progesterone receptor status on survival

EE Lower, EL Glass, DA Bradley, R Blau… - Breast cancer research …, 2005 - Springer
Hormone responsive breast cancer is usually determined by the presence of estrogen
receptors (ER) or progesterone receptors (PR) on primary invasive breast cancers. Adjuvant …

Immunohistochemical evaluation of hormone receptor status for predicting response to endocrine therapy in metastatic breast cancer

H Yamashita, Y YAndo, M Nishio, Z Zhang… - Breast cancer, 2006 - jstage.jst.go.jp
Background: The importance of establishing hormone receptor status of tumors for the
treatment of women with hormone receptor-positive breast cancer has been emphasized …

Discordance in hormone receptor status in breast cancer during tumor progression.

E Karlsson, LS Lindstrom, U Wilking… - Journal of Clinical …, 2010 - ascopubs.org
1009 Background: In the metastatic situation therapy management is often based on primary
tumor characteristics such as estrogen receptor (Er) and progesterone receptor (Pr) status …

Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases

LDC Hoefnagel, CB Moelans, SL Meijer… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Changes in the receptor profile of primary breast cancers to their
metastases (receptor conversion) have been described for the estrogen receptor α (ERα) …

Stability of estrogen receptor status in breast carcinoma: a comparison between primary and metastatic tumors with regard to disease course and intervening systemic …

Y Gong, EY Han, M Guo, L Pusztai, N Sneige - Cancer, 2011 - Wiley Online Library
BACKGROUND: The purposes of this study were to address a persistent controversy as to
whether the ER status of a primary tumor remains stable during progression to metastasis …

[HTML][HTML] Receptor conversion in metastatic breast cancer: a prognosticator of survival

X Meng, S Song, ZF Jiang, B Sun, T Wang, S Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Objective This retrospective study investigated the association between hormone receptor
(HR) conversion and survival in breast cancer patients. Methods Estrogen receptor (ER) and …

Discordance of the estrogen receptor and HER-2/neu in breast cancer from primary lesion to first and second metastatic site

EE Lower, S Khan, D Kennedy… - Breast Cancer: Targets …, 2017 - Taylor & Francis
Background Hormone receptor and HER-2/neu discordance between the primary lesion and
first metastasis has been reported. This study was performed to determine further biomarker …

Changes in estrogen receptor, progesterone receptor and Her-2/neu status with time: discordance rates between primary and metastatic breast cancer

RJ Broom, PA Tang, C Simmons, L Bordeleau… - Anticancer …, 2009 - ar.iiarjournals.org
Background: Changes in the receptor profile between primary and metastatic breast cancer
tissue have been suggested. The degree of hormone receptor discordance in archival …

Loss of estrogen receptor in recurrent breast cancer is associated with poor response to endocrine therapy.

T Kuukasjärvi, J Kononen, H Helin, K Holli… - Journal of Clinical …, 1996 - ascopubs.org
PURPOSE Up to 30% to 40% of metastases from hormone receptor-positive primary breast
cancer do not respond to endocrine therapy. We studied how often hormone receptor status …

Discordances in estrogen receptor status, progesterone receptor status, and HER2 status between primary breast cancer and metastasis

E Curtit, V Nerich, L Mansi, L Chaigneau, L Cals… - The …, 2013 - academic.oup.com
Background. The primary aim of this retrospective study was to investigate intraindividual
correlation of estrogen receptor (ER) status, progesterone receptor (PR) status, and HER2 …