Objective: Weight-loss intervention through diet modification has been widely used to
improve obesity-related hyperglycemia; however, little is known about whether genetic …

Background: Diet interventions have shown effectiveness in improving diabetes risk factors;
however, little is known about whether the effects of diet intervention are different according …

Purpose Obesity is a heterogeneous condition and distinct adiposity subtypes may
differentially affect type 2 diabetes risk. We assessed relations between genetically …

Clinically relevant weight loss is achievable through lifestyle modification, but unintentional
weight regain is common. We investigated whether recently discovered genetic variants …

Importance Dietary modification remains key to successful weight loss. Yet, no one dietary
strategy is consistently superior to others for the general population. Previous research …

Weight loss (WL) differences between isocaloric high-carbohydrate and high-fat diets are
generally small; however, individual WL varies within diet groups. Genotype patterns may …

Aim To investigate whether the genetic risk score (GRS) for lean body mass (LBM) modified
the effects of weight‐loss diets on changes in appetite and adiposity among overweight and …

Background—Common genetic variants in the insulin receptor substrate 1 (IRS1) gene have
been recently associated with insulin resistance and hyperinsulinemia. We examined …

Obesity and related co-morbidities are major health problems throughout the world. Dietary
interventions are the most common strategies employed for weight loss in overweight and …

Background: Differences in the interindividual response to dietary intervention could be
modified by genetic variation in nutrient-sensitive genes. Objective: This study examined …