Genes can be expressed at a wide range of levels, and they show different degrees of cross-
species conservation. We compared gene expression levels to gene conservation by …

IN the fission yeast Schizosaccharomyces pombe, the double-stranded chromosomal break
(DSB) at the mating-type locus (mat1) initiates recombination during mating-type switching1 …

How cells polarize in response to external cues is a fundamental biological problem. For
mating, yeast cells orient growth toward the source of a pheromone gradient produced by …

Conditional mutants are a vital tool for analysis of gene function. The use of temperature-
sensitive mutants in Schizosaccharomyces pombe has significantly promoted understanding …

Fungi are a diverse group of organisms with a huge variation in reproductive strategy. While
almost all species can reproduce sexually, many reproduce asexually most of the time …

In multicellular organisms, there is a potential risk that cheating mutants gain access to the
germline. Development from a single-celled zygote resets relatedness among cells to its …

Background The fission yeast Schizosaccharomyces pombe is a popular genetic model
organism with powerful experimental tools. The thiamine-regulatable nmt1 promoter and …

The fission yeast Schizosaccharomyces pombe is an important model organism for the study
of eukaryotic molecular and cellular biology. Studies of S. pombe, together with studies of its …

In response to nitrogen starvation in the presence of a poor carbon source, diploid cells of
the yeast Saccharomyces cerevisiae undergo meiosis and package the haploid nuclei …

While the fission yeast is a powerful model of eukaryote biology, there have been few
studies of quantitative genetics, phenotypic or genetic diversity. Here I survey the small …