Interictal spikes and epileptic seizures: their relationship and underlying rhythmicity
PJ Karoly, DR Freestone, R Boston, DB Grayden… - Brain, 2016 - academic.oup.com
We report on a quantitative analysis of electrocorticography data from a study that acquired
continuous ambulatory recordings in humans over extended periods of time. The objectives …
continuous ambulatory recordings in humans over extended periods of time. The objectives …
Relationships between interictal spiking and seizures: human and experimental evidence
J Gotman - Canadian journal of neurological sciences, 1991 - cambridge.org
Epileptic seizures of focal origin often occur unpredictably as do interictal spikes. It is often
assumed that spikes increase prior to seizures of focal origin and that antiepileptic …
assumed that spikes increase prior to seizures of focal origin and that antiepileptic …
Do interictal spikes drive epileptogenesis?
K Staley, JL Hellier, FE Dudek - The Neuroscientist, 2005 - journals.sagepub.com
Interictal spikes are periodic, very brief bursts of neuronal activity that are observed in the
electroencephalogram of patients with chronic epilepsy. These spikes are useful …
electroencephalogram of patients with chronic epilepsy. These spikes are useful …
Interictal spiking increases after seizures but does not after decrease in medication
J Gotman, DJ Koffler - Electroencephalography and clinical …, 1989 - Elsevier
In patients with focal epilepsy, EEG spike rate fluctuates considerably over time. We had
previously shown that seizure occurrence played an important role in these fluctuations. We …
previously shown that seizure occurrence played an important role in these fluctuations. We …
Clinical relevance of quantified intracranial interictal spike activity in presurgical evaluation of epilepsy
A Hufnagel, M Dümpelmann, J Zentner, O Schijns… - …, 2000 - Wiley Online Library
Purpose: Electrocorticograms of 32 patients with medically intractable seizures, recorded
through intracranial electrodes, were retrospectively analyzed. The objective was to assess …
through intracranial electrodes, were retrospectively analyzed. The objective was to assess …
Interictal spikes on intracranial recording: behavior, physiology, and implications
SS Spencer, II Goncharova, RB Duckrow… - …, 2008 - Wiley Online Library
Purpose: The physiological, pathological, and clinical meaning of interictal spikes (IISs)
remains controversial. We systematically analyzed the frequency, occurrence, and …
remains controversial. We systematically analyzed the frequency, occurrence, and …
Interictal spikes: harbingers or causes of epilepsy?
KJ Staley, A White, FE Dudek - Neuroscience letters, 2011 - Elsevier
Interictal spikes are brief paroxysmal electrographic discharges observed between
spontaneous recurrent seizures in epileptic patients. The relationship between interictal …
spontaneous recurrent seizures in epileptic patients. The relationship between interictal …
Does interictal spiking change prior to seizures?
A Katz, DA Marks, G McCarthy, SS Spencer - … and clinical neurophysiology, 1991 - Elsevier
We studied 10 patients with intractable epilepsy being evaluated for epilepsy surgery for
preictal changes in spiking. All patients were implanted with intracranial electrodes and …
preictal changes in spiking. All patients were implanted with intracranial electrodes and …
Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset
EC Conrad, SB Tomlinson, JN Wong, KF Oechsel… - Brain, 2020 - academic.oup.com
The location of interictal spikes is used to aid surgical planning in patients with medically
refractory epilepsy; however, their spatial and temporal dynamics are poorly understood. In …
refractory epilepsy; however, their spatial and temporal dynamics are poorly understood. In …
Do interictal spikes sustain seizures and epileptogenesis?
Interictal spiking is seen in the EEG of epileptic patients between seizures. To date, the roles
played by interictal events in seizure occurrence and in epileptogenesis remain elusive …
played by interictal events in seizure occurrence and in epileptogenesis remain elusive …