A placenta for life

R John, M Hemberger - Reproductive biomedicine online, 2012 - Elsevier
The chorioallantoic placenta is the defining organ of eutherians that has enabled prolonged
intrauterine gestation. As such, normal placental development and function are essential for …

Placenta: the forgotten organ

E Maltepe, SJ Fisher - Annual review of cell and developmental …, 2015 - annualreviews.org
The placenta sits at the interface between the maternal and fetal vascular beds where it
mediates nutrient and waste exchange to enable in utero existence. Placental cells …

How to make a placenta: mechanisms of trophoblast cell differentiation in mice–a review

JC Cross - Placenta, 2005 - Elsevier
The word placenta is derived from the Latin term meaning 'flat cake'. Despite the rather
humble name, the placenta is an amazing organ that forms both the interface for selective …

[PDF][PDF] Genes, development and evolution of the placenta

JC Cross, D Baczyk, N Dobric, M Hemberger… - Placenta, 2003 - researchgate.net
Comparing the placenta from one species to another can be a challenging task. On one
hand, the gross anatomy of the placenta is at least superficially rather different among …

Epigenetic features of the mouse trophoblast

PJ Rugg-Gunn - Reproductive biomedicine online, 2012 - Elsevier
Trophoblast cells are required for the growth and survival of the fetus during pregnancy, and
failure to maintain appropriate trophoblast regulation is associated with placental …

[HTML][HTML] Human placental development and function

T Cindrova-Davies, AN Sferruzzi-Perri - Seminars in cell & developmental …, 2022 - Elsevier
The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …

Development of the human placenta

MY Turco, A Moffett - Development, 2019 - journals.biologists.com
The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

The placenta: epigenetic insights into trophoblast developmental models of a generation-bridging organ with long-lasting impact on lifelong health

M Hemberger, W Dean - Physiological Reviews, 2023 - journals.physiology.org
The placenta is a unique organ system that functionally combines both maternal and fetal
cell types with distinct lineage origins. Normal placentation is critical for developmental …

Placental function in development and disease

JC Cross - Reproduction, Fertility and development, 2005 - CSIRO Publishing
The placenta is an organ that clinicians and embryologists would all agree is important for
pregnancy success. Unfortunately, however, they too often ignore it when they are exploring …

Unique features and emerging in vitro models of human placental development

S Shibata, EH Kobayashi, N Kobayashi… - Reproductive …, 2020 - Wiley Online Library
Background The placenta is an essential organ for the normal development of mammalian
fetuses. Most of our knowledge on the molecular mechanisms of placental development has …