B antagonists eye drops are most effective for the treatment of chronic open angle
glaucoma. By this way of administration they have a very good systemic bioavailability …

Beta-blocker eyedrops used on asthmatic patients are known to enhance asthma which is,
as chronic bronchitis, an obstructive disease of the lung, and an authentic …

Topical β-blockers reduce the intraocular pressure (IOP) by blockade of sympathetic nerve
endings in the ciliary epithelium causing a fall in aqueous humour production. Two types of …

To evaluate the effects of two beta-adrenergic blocking agents on cardiopulmonary function,
we investigated two topical ophthalmologic preparations, betaxolol 1% and timolol 0.5%, in …

A double-blind cross-over study was carried out on 15 glaucoma patients so as to verify the
effects of three the beta blockers, beta-1 selective betaxolol, non-selective timolol and …

1. The inadvertent administration of timolol to asthmatic patients continues to cause
occasional severe and even fatal attacks of asthma. The (R)‐enantiomer of timolol, L …

The R‐enantiomer of timolol, L‐714,465, is considerably less potent as a beta 1‐and beta 2‐
adrenoceptor antagonist in animals than timolol, whilst only slightly less potent in reducing …

Glaucoma is described, and the chemistry, pharmacology, pharmacokinetics, clinical
efficacy, adverse effects, and dosage and administration of betaxolol and levobunolol in …

The autonomic nervous system is divided into the parasympathetic and sympathetic
systems, with three types of adrenergic receptors: alpha (smooth muscle contraction), beta 1 …

Early clinical studies revealed that timolol and other topical β blockers were effective in
reducing intra‐ocular pressure, without the side effects associated with other antiglaucoma …