Replication of obesity and associated signaling pathways through transfer of microbiota from obese-prone rats

FA Duca, Y Sakar, P Lepage, F Devime, B Langelier… - Diabetes, 2014 - Am Diabetes Assoc
Aberrations in gut microbiota are associated with metabolic disorders, including obesity.
However, whether shifts in the microbiota profile during obesity are a characteristic of the …

Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives

L Sun, L Ma, Y Ma, F Zhang, C Zhao, Y Nie - Protein & cell, 2018 - academic.oup.com
Concern about health risks associated with rising obesity has become nearly universal, with
the mean body mass index (BMI) and the prevalence of obese and overweight individuals …

High fat diet drives obesity regardless the composition of gut microbiota in mice

S Rabot, M Membrez, F Blancher, B Berger, D Moine… - Scientific reports, 2016 - nature.com
The gut microbiota is involved in many aspects of host physiology but its role in body weight
and glucose metabolism remains unclear. Here we studied the compositional changes of …

Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice

A Everard, V Lazarevic, M Derrien, M Girard… - …, 2011 - Am Diabetes Assoc
OBJECTIVE To investigate deep and comprehensive analysis of gut microbial communities
and biological parameters after prebiotic administration in obese and diabetic mice …

Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis

N Jiao, SS Baker, CA Nugent… - Physiological …, 2018 - journals.physiology.org
A number of studies have associated obesity with altered gut microbiota, although results
are discordant regarding compositional changes in the gut microbiota of obese animals …

Changes in gut microbiota in rats fed a high fat diet correlate with obesity-associated metabolic parameters

V Lecomte, NO Kaakoush, CA Maloney, M Raipuria… - PloS one, 2015 - journals.plos.org
The gut microbiota is emerging as a new factor in the development of obesity. Many studies
have described changes in microbiota composition in response to obesity and high fat diet …

Dietary uncoupling of gut microbiota and energy harvesting from obesity and glucose tolerance in mice

MJ Dalby, AW Ross, AW Walker, PJ Morgan - Cell reports, 2017 - cell.com
Evidence suggests that altered gut microbiota composition may be involved in the
development of obesity. Studies using mice made obese with refined high-fat diets have …

Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice

P Zhang, Y Yu, Y Qin, Y Zhou, R Tang, Q Wang… - The Journal of …, 2019 - Elsevier
Obesity is underpinned by both genetic and environmental factors, including a high-
saturated-fat diet. Some mice develop diet-induced obesity (DIO), but others remain diet …

Gut microbiota-dependent modulation of energy metabolism

CN Heiss, LE Olofsson - Journal of innate immunity, 2018 - karger.com
The gut microbiota has emerged as an environmental factor that modulates the host's
energy balance. It increases the host's ability to harvest energy from the digested food, and …

[HTML][HTML] Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice

X Ke, A Walker, SB Haange, I Lagkouvardos, Y Liu… - Molecular …, 2019 - Elsevier
Objective The gut microbiota is an important influencing factor of metabolic health. Although
dietary interventions with probiotics, prebiotics, and synbiotics can be effective means to …