Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
DJ Hicklin, LM Ellis - Journal of clinical oncology, 2005 - ascopubs.org
New blood vessel formation (angiogenesis) is a fundamental event in the process of tumor
growth and metastatic dissemination. Hence, the molecular basis of tumor angiogenesis has …
growth and metastatic dissemination. Hence, the molecular basis of tumor angiogenesis has …
Pivotal role of vascular endothelial growth factor pathway in tumor angiogenesis
SH Lee, D Jeong, YS Han… - Annals of surgical …, 2015 - synapse.koreamed.org
The shaping of new blood vessels is a significant event in cancer growth and metastasis.
Therefore, the molecular system of cancer angiogenesis has garnered considerable interest …
Therefore, the molecular system of cancer angiogenesis has garnered considerable interest …
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
N Ferrara, KJ Hillan, HP Gerber… - Nature reviews Drug …, 2004 - nature.com
The existence of factors that stimulate blood vessel growth, thereby recruiting a neovascular
supply to nourish a growing tumour, was postulated many decades ago, although the …
supply to nourish a growing tumour, was postulated many decades ago, although the …
Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in tumor angiogenesis and malignancies
CR Pradeep, ES Sunila… - Integrative cancer …, 2005 - journals.sagepub.com
Angiogenesis is a process by which new blood vessels are formed from preexisting vessels.
New blood vessel formation by angiogenesis involves the degradation of extra-cellular …
New blood vessel formation by angiogenesis involves the degradation of extra-cellular …
Vascular endothelial growth factor as a target for anticancer therapy
N Ferrara - The oncologist, 2004 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: Explain
the biology of angiogenesis. Identify the role of VEGF in normal and tumor angiogenesis …
the biology of angiogenesis. Identify the role of VEGF in normal and tumor angiogenesis …
The critical role of vascular endothelial growth factor in tumor angiogenesis
A Amini, S Masoumi Moghaddam… - Current cancer drug …, 2012 - ingentaconnect.com
Angiogenesis is the formation of new blood vessels from the pre-existing vasculature.
Besides its role in normal physiology, angiogenesis is significantly involved in many …
Besides its role in normal physiology, angiogenesis is significantly involved in many …
Vascular endothelial growth factor signaling pathways: therapeutic perspective
M Kowanetz, N Ferrara - Clinical Cancer Research, 2006 - AACR
The establishment of a vascular supply is one of the earliest and most important events
occurring during embryonic development. Growth and maturation of a functional vascular …
occurring during embryonic development. Growth and maturation of a functional vascular …
Targeting angiogenesis in cancer: clinical development of bevacizumab
DJ Kerr - Nature clinical practice Oncology, 2004 - nature.com
The importance of vascular endothelial growth factor (VEGF) as a regulator of normal and
tumor blood vessel growth has been increasingly characterized over the past two decades …
tumor blood vessel growth has been increasingly characterized over the past two decades …
Vascular endothelial growth factor signaling pathway as an emerging target in hematologic malignancies
AF List - The Oncologist, 2001 - academic.oup.com
Angiogenesis is important in a variety of physiologic and pathologic disorders. It is a central
element in embryogenesis, ovulation, wound healing, diabetic retinopathy, and rheumatoid …
element in embryogenesis, ovulation, wound healing, diabetic retinopathy, and rheumatoid …
Vascular endothelial growth factor (VEGF) signaling in tumour vascularization: potential and challenges
K Sivaraman Siveen, K Prabhu… - Current vascular …, 2017 - ingentaconnect.com
Angiogenesis is defined as the physiological process by which new blood vessels develop
from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis …
from pre-existing vessels; either by sprouting or intussusception. Inhibition of angiogenesis …