Expression of differentiated function in neoplasms

RG McKinnell - The Pathobiology of Neoplasia, 1989 - Springer
Abstract “Once a cancer cell, always a cancer cell” is classic dogma that arose quite
naturally from observation of the usual intractable course of cancer in human beings. 1 Yet …

Differentiation potential of cancer cells

NE Fusenig, D Breitkreutz, P Boukamp - Human cancer in primary culture …, 1991 - Springer
Differentiation Potential of Cancer Cells Page 1 Chapter 3 Differentiation Potential of Cancer
Cells NORBERT E. FUSENIG, DIRK BREITKREUTZ and PETRA BOUKAMP Contents …

Differential retention of tumor‐and differentiation‐suppressor functions in cells derived from a human squamous cell carcinoma

DR Jaffe, Y Montero‐Puerner, MA Beckett… - Molecular …, 1992 - Wiley Online Library
Three morphologically distinct cell lines—F. 2a, V, and B. 2—were isolated from a single
human squamous cell carcinoma. Although all three cell lines can grow indefinitely in …

Developmental gene expression in cancer

KH Ibsen, WH Fishman - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1979 - Elsevier
The tendency for malignancies to lose the final differentiated morphology of their tissue of
origin (ie to dedifferentiate) was recognized some 150 years ago (cf. Ref. 1); more than 30 …

Oncogenes and the nature of malignancy

I Buckley - Advances in cancer research, 1988 - Elsevier
Publisher Summary This chapter provides a brief overview of the well-established structural
and behavioral features of malignancy. The chapter focuses on the nature of the …

Molecular biology of tumor cells

B Wahren, G Holm, S Hammarstom, P Perlmann - 1985 - osti.gov
This book contains four sections, each consisting of several papers. The section titles are:
Activated Genes and Oncogenes; Promotors and Growth Factors for Induction of Cancer; …

Positive mediators of cell proliferation in neoplastic transformation

JN Welch, SA Chrysogelos - The Molecular Basis of Human Cancer, 2002 - Springer
Cancer is not a single disease, but a collection of diseases all of which are related by a
common root cause: the loss of controlled cell growth. Cancer begins as a clonal disease …

Differentiation and cancer

G Barry Pierce, LD Johnson - In vitro, 1971 - Springer
Cancer is discussed from a standpoint of a postembryonic differentiation. A differentiation
requires the interaction of an exogenous inductive stimulus with competent precursor cell …

[引用][C] Differentiation and cancer

MD Mason - European Journal of Cancer, 1992 - Elsevier
NORMAL TISSUE growth and renewal depends on cellular differentiation from a pool of
stem cells, undifferentiated cells which are the origin of the mature cells that character&e an …

Cancer: the product of abortive redifferentiation

JH Coggin Jr - Immunological Aspects of Cancer, 1978 - Springer
Cancers are the most studied yet the least understood of all the diseases of man. Our
ignorance about how to pragmatically control cancers results from our lack of understanding …