Cells in the central nervous system rely almost exclusively on aerobic metabolism. Oxygen
deprivation, such as injury-associated ischemia, results in detrimental apoptotic and necrotic …

We studied the effect of hyperbaric oxygen (HBO) preconditioning on the molecular
mechanisms of neuroprotection in a rat focal cerebral ischemic model. Seventy-two male …

Intracranial pressure (ICP) was monitored to evaluate the therapeutic effect of hyperbaric
oxygen (HBO2) treatment following traumatic brain injury (TBI). This subject is controversial …

Aim To study the mechanisms of how hyperbaric oxygen treatment (HBOT) reduced
neuronal apoptosis following forebrain ischemia reperfusion. Methods Changes of the …

Hypoxic preconditioning (HPC) exerts a protective effect against hypoxic/ischemic brain
injury, and one mechanism explaining this effect may involve the upregulation of hypoxia …

We previously reported in rats that preconditioning with hyperbaric oxygen (HBO; 100% O2
3.5-atomsphere absolute (ATA), 1 h/day for 5 days) provided neuroprotection against …

Secondary cerebral hypoxia has recently been shown to play an important role in the
outcome of patients suffering from traumatic brain injury (TBI). However, the precise …

Background—Hyperbaric oxygenation (HBO) after focal cerebral ischemia reduces infarct
size and improves outcome when applied early after stroke. Here, we evaluated effects of …

Traumatic brain injury (TBI) causes significant mortality in most developing countries
worldwide. At present, it is imperative to identify a treatment to address the devastating post …

This study was aimed at understanding the effect of intermittent hypobaric hypoxia
preconditioning (IHHP) on neuroglobin (NGB) and Bcl-2 expression in the hippocampal CA1 …