Peripheral, But Not Central, Administration of Adiponectin Reduces Visceral Adiposity and Upregulates the Expression of Uncoupling Protein in Agouti Yellow (Ay/a) …

T Masaki, S Chiba, T Yasuda, T Tsubone, T Kakuma… - Diabetes, 2003 - Am Diabetes Assoc
To examine the peripheral and central roles of adiponectin in energy intake and
expenditure, we investigated the effects of adiponectin on food intake, adiposity, sympathetic …

Energy intake and adiponectin gene expression

L Qiao, B Lee, B Kinney, H Yoo… - American Journal of …, 2011 - journals.physiology.org
Hypoadiponectinemia and decreased adiponectin gene expression in white adipose tissue
(WAT) have been well observed in obese subjects and animal models. However, the …

Physiological difference between obese (fa/fa) Zucker rats and lean Zucker rats concerning adiponectin

F Oana, H Takeda, K Hayakawa, A Matsuzawa… - Metabolism, 2005 - Elsevier
Obese (fa/fa) Zucker rat is a spontaneous genetic obesity model and, by comparison with
lean Zucker rat, exhibits hyperphagia, hyperinsulinemia, and hyperlipidemia. The aim of this …

Overexpression of adiponectin targeted to adipose tissue in transgenic mice: impaired adipocyte differentiation

IB Bauche, SA El Mkadem, AM Pottier, M Senou… - …, 2007 - academic.oup.com
Adiponectin (ApN) is an adipokine whose expression and plasma levels are inversely
related to obesity and insulin-resistant states. Chronic repercussions of ApN treatment or …

Adipokines identified as new downstream targets for adiponectin: lessons from adiponectin-overexpressing or-deficient mice

Q Ge, L Ryken, L Noel, E Maury… - American Journal of …, 2011 - journals.physiology.org
Adipokines play a central role in the pathogenesis of the metabolic syndrome. Among them,
adiponectin (ApN), a master regulator of immune and fuel homeostasis, is decreased …

Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice

JW Bullen Jr, S Bluher, T Kelesidis… - American Journal of …, 2007 - journals.physiology.org
Adiponectin and its receptors play an important role in energy homeostasis and insulin
resistance, but their regulation remains to be fully elucidated. We hypothesized that high-fat …

Long‐term central infusion of adiponectin improves energy and glucose homeostasis by decreasing fat storage and suppressing hepatic gluconeogenesis without …

S Park, DS Kim, DY Kwon… - Journal of …, 2011 - Wiley Online Library
Adiponectin is known to be an anti‐diabetic adipocytokine. However, the action mechanism
by which it produces this effect remains controversial. In the present study, we investigated …

A fat-enriched, glucose-enriched diet markedly attenuates adiponectin mRNA levels in rat epididymal adipose tissue

EK Naderali, D Estadella, M Rocha… - Clinical …, 2003 - portlandpress.com
Adiponectin levels are decreased in subjects with obesity, diabetes and coronary artery
disease. In the present study, we have investigated whether the decrease in the levels and …

A high‐fat diet has a tissue‐specific effect on adiponectin and related enzyme expression

M Barnea, A Shamay, AH Stark, Z Madar - Obesity, 2006 - Wiley Online Library
Objective: This study was designed to test whether adiponectin plays a role in diet‐induced
obesity and insulin resistance and acts as a mediator to induce or inhibit specific metabolic …

Adiponectin downregulates its own production and the expression of its AdipoR2 receptor in transgenic mice

IB Bauche, SA El Mkadem, R Rezsohazy… - Biochemical and …, 2006 - Elsevier
Adiponectin (ApN) is an adipokine whose expression and plasma levels are inversely
related to obesity and insulin-resistant states. The in vivo effects of a chronic expression of …