Identification of diagnostic biomarkers and therapeutic targets in peripheral immune landscape from coronary artery disease

X Feng, Y Zhang, M Du, S Li, J Ding, J Wang… - Journal of Translational …, 2022 - Springer
Background Peripheral biomarkers are increasingly vital non-invasive methods for
monitoring coronary artery disease (CAD) progression. Their superiority in early detection …

Immune-related potential biomarkers and therapeutic targets in coronary artery disease

C Liu, J Liu, Y Zhang, X Wang, Y Guan - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Background Coronary artery disease (CAD) is a complex illness with unknown
pathophysiology. Peripheral biomarkers are a non-invasive method required to track the …

Identification and validation of immune-related genes diagnostic for progression of atherosclerosis and diabetes

Y Fu, L Xu, H Zhang, N Ding, J Zhang… - Journal of …, 2023 - Taylor & Francis
Background Atherosclerosis and type 2 diabetes mellitus contribute to a large part of
cardiovascular events, but the underlying mechanism remains unclear. In this study, we …

Identification of potential therapeutic targets for atherosclerosis by analysing the gene signature related to different immune cells and immune regulators in …

Y Shen, L Xu, X Tang, C Lin, D Yan, S Xue… - BMC Medical …, 2021 - Springer
Background Atherosclerosis is a chronic inflammatory disease that affects multiple arteries.
Numerous studies have shown the inherent immune diversity in atheromatous plaques and …

Identification of immune-related genes in patients with acute myocardial infarction using machine learning methods

X Zhu, T Yin, T Zhang, Q Zhu, X Lu… - Journal of …, 2022 - Taylor & Francis
Objective This study aimed to analyze immune-related genes and immune cell components
in the peripheral blood of patients with acute myocardial infarction (AMI). Methods Six …

Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via …

J Xu, C Chen, Y Yang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Objective To explore the differentially expressed genes (DEGs) along with infiltrating
immune cells landscape and their potential mechanisms in the progression of …

Collapsing the list of myocardial infarction-related differentially expressed genes into a diagnostic signature

G Osmak, N Baulina, P Koshkin, O Favorova - Journal of Translational …, 2020 - Springer
Background Myocardial infarction (MI) is one of the most severe manifestations of coronary
artery disease (CAD) and the leading cause of death from non-infectious diseases …

The integrated analysis identifies three critical genes as novel diagnostic biomarkers involved in immune infiltration in atherosclerosis

Z Ye, X Wang, Y Lv, X Wang, Y Cui - Frontiers in Immunology, 2022 - frontiersin.org
Atherosclerosis (AS), a chronic inflammatory disease of the blood vessels, is the primary
cause of cardiovascular disease, the leading cause of death worldwide. This study aimed to …

Predicting diagnostic gene biomarkers associated with immune infiltration in patients with acute myocardial infarction

E Zhao, H Xie, Y Zhang - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
Objective: The present study was designed to identify potential diagnostic markers for acute
myocardial infarction (AMI) and determine the significance of immune cell infiltration in this …

Identifying patterns of immune related cells and genes in the peripheral blood of acute myocardial infarction patients using a small cohort

PF Zheng, QC Zou, LZ Chen, P Liu, ZY Liu… - Journal of Translational …, 2022 - Springer
Background The immune system plays a vital role in the pathophysiology of acute
myocardial infarction (AMI). However, the exact immune related mechanism is still unclear …