New horizons for imaging lymphatic function

R Sharma, JA Wendt, JC Rasmussen… - Annals of the New …, 2008 - Wiley Online Library
In this review, we provide a comprehensive summary of noninvasive imaging modalities
used clinically for the diagnosis of lymphatic diseases, new imaging agents for assessing …

Lymphatic imaging in humans with near-infrared fluorescence

JC Rasmussen, IC Tan, MV Marshall, CE Fife… - Current opinion in …, 2009 - Elsevier
While the lymphatic system is increasingly associated with diseases of prevalence, study of
these diseases is difficult owing to the paucity of imaging techniques with the sensitivity and …

Noninvasive quantitative imaging of lymph function in mice

S Kwon, EM Sevick-Muraca - Lymphatic Research and Biology, 2007 - liebertpub.com
Background: Whereas functional lymph imaging in rodents is imperative for drug discovery
of lymph therapeutics, noninvasive imaging of propulsive lymph function in rodents has not …

The role of lymphatics in cancer as assessed by near-infrared fluorescence imaging

JC Rasmussen, S Kwon, EM Sevick-Muraca… - Annals of biomedical …, 2012 - Springer
The lymphatic system is the secondary circulatory system responsible for fluid homeostasis
and protein transport in the body. In addition, because the lymphatic system provides a …

Imaging peripheral lymphatic dysfunction in chronic conditions

EM Sevick-Muraca, CE Fife, JC Rasmussen - Frontiers in Physiology, 2023 - frontiersin.org
The lymphatics play important roles in chronic diseases/conditions that comprise the bulk of
healthcare worldwide. Yet the ability to routinely image and diagnose lymphatic dysfunction …

Sensitivity analysis of near-infrared functional lymphatic imaging

M Weiler, T Kassis, JB Dixon - Journal of biomedical optics, 2012 - spiedigitallibrary.org
Near-infrared imaging of lymphatic drainage of injected indocyanine green (ICG) has
emerged as a new technology for clinical imaging of lymphatic architecture and …

In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging

C Chong, F Scholkmann, SB Bachmann, P Luciani… - Scientific reports, 2016 - nature.com
Techniques to image lymphatic vessel function in either animal models or in the clinic are
limited. In particular, imaging methods that can provide robust outcome measures for …

Human lymphatic architecture and dynamic transport imaged using near-infrared fluorescence

JC Rasmussen, IC Tan, MV Marshall, KE Adams… - Translational …, 2010 - Elsevier
BACKGROUND: Although the importance of lymphatic function is well recognized, the lack
of real-time imaging modalities limits our understanding of its role in many diseases. In a …

Preclinical lymphatic imaging

F Zhang, G Niu, G Lu, X Chen - Molecular Imaging and Biology, 2011 - Springer
Noninvasive in vivo imaging of lymphatic vessels and lymphatic nodes is expected to fulfill
the purpose of analyzing lymphatic vessels and their function, understanding molecular …

Functional lymphatic imaging in tumor-bearing mice

S Kwon, EM Sevick-Muraca - Journal of immunological methods, 2010 - Elsevier
The lymphatic system provides a route for dissemination of metastatic cancer cells. Yet to
date transient changes in lymphatic drainage pathways and function as a result of tumor …