Akt is a serine/threonine protein kinase that is activated by a number of growth factors and
cytokines in a phosphatidylinositol-3 kinase–dependent manner. Although antiapoptotic …

The mammalian serine/threonine Akt kinases comprise three closely related isoforms: Akt1,
Akt2 and Akt3. Akt activation has been implicated in both normal and disease processes …

Akt, also known as Protein kinase B (PKB), regulates essential cellular functions such as
migration, proliferation, differentiation, apoptosis, and metabolism. Akt influences the …

The PI3K/Akt pathway is necessary for several key endothelial cell (EC) functions, including
cell growth, migration, survival, and vascular tone. However, existing literature supports the …

AKT is a central signaling molecule in regulating cell survival, proliferation, tumor growth
and angiogenesis. Upstream components of AKT signaling pathway such as PI3K, PTEN …

Akt, or protein kinase B, is a multifunctional serine-threonine protein kinase implicated in a
diverse range of cellular functions including cell metabolism, survival, migration, and gene …

Akt kinase, a member of AGC kinases, is important in many cellular functions including
proliferation, migration, cell growth and metabolism. There are three known Akt isoforms …

Regulation of endothelial cell apoptosis is a critical modulator of normal and pathological
angiogenesis. In this study, we examined the role of the protein kinase Akt/PKB in …

The serine/threonine kinase Akt, also named protein kinase B, plays a central role in
promoting the survival of a wide range of cell types. 1 In this issue of Circulation Research …

Akt/PKB is a key master regulator of a wide range of physiological functions including
metabolism, proliferation, survival, growth, angiogenesis and migration and invasion. The …