Killer-cell immunoglobulin-like receptor (KIR) genes are a polymorphic family expressed on
NK cells, and “senescent” CD28− T cells implicated in cardiovascular disease. KIR …

With increasing age, T cells gain expression of killer immunoglobulin–like receptors (KIRs)
that transmit negative signals and dampen the immune response. KIR expression is induced …

Variegated expression of killer Ig-like receptors (KIR) in human NK cells is a stochastic
process exclusive to subsets of mature NK cells and CD8+ T cells. Allele-specific KIR …

Killer immunoglobulin-like receptors (KIR) bind self–major histocompatibility complex class I
molecules, allowing natural killer (NK) cells to recognize aberrant cells that have down …

Killer Ig-like receptor (KIR) expression is mostly restricted to NK cells controlling their
activation. With increasing age, KIRs are expressed on T cells and contribute to age-related …

NK cells as a component of the innate immune system provide a first line of defense against
viral infections and malignancies. Killer immunoglobulin-like receptors (KIRs) are a …

Mature human NK lymphocytes express the highly homologous killer Ig-like receptor (KIR)
genes in a stochastic fashion, and KIR transcription precisely correlates with allele-specific …

Human NK cells are characterized by the expression of surface receptors of the killer cell Ig-
like receptor (KIR) family, which are involved in the specific recognition of pathogenic target …

The generation of killer cell Ig-like receptor (KIR) expression patterns in NK cells involves
variegated silencing of KIR genes by DNA methylation. To identify regulatory elements …

T cells from lupus patients have hypomethylated DNA and overexpress genes normally
suppressed by DNA methylation that contribute to disease pathogenesis. We found that …