Conversion of angiotensin I to angiotensin II in dog isolated renal artery: role of two different angiotensin II-generating enzymes
T Okamura, H Okunishi, K Ayajiki… - Journal of cardiovascular …, 1990 - journals.lww.com
The functional role of the endothelium in conversion of angiotensin (Ang) I to Ang II was
studied in helical strips of dog renal arteries. In the arteries precontracted with PGF2 [alpha] …
studied in helical strips of dog renal arteries. In the arteries precontracted with PGF2 [alpha] …
Evidence for a putatively new angiotensin II-generating enzyme in the vascular wall
H Okunishi, M Miyazaki, N Toda - Journal of hypertension, 1984 - journals.lww.com
An inhibitor of angiotensin I (ANG I) converting enzyme, SA446, reduced the response to
ANG I of blood vessels isolated from dogs and monkeys, but did not abolish the response …
ANG I of blood vessels isolated from dogs and monkeys, but did not abolish the response …
Different angiotensin II-forming pathways in human and rat vascular tissues
S Takai, M Sakaguchi, D Jin, M Yamada, K Kirimura… - Clinica chimica acta, 2001 - Elsevier
We studied the angiotensin II-forming pathways in extracts from human and rat vascular
tissues. In the extract from human artery, angiotensin I mainly converted to two products …
tissues. In the extract from human artery, angiotensin I mainly converted to two products …
The angiotensin converting enzyme in the kidney
F Alhenc-Gelas, T Baussant, C Hubert… - Journal of …, 1989 - journals.lww.com
Immunohistochemical studies and experiments with microdissected nephron segments
indicate that the angiotensin I converting enzyme (ACE) in the kidney is expressed in the …
indicate that the angiotensin I converting enzyme (ACE) in the kidney is expressed in the …
Characteristics of angiotensin converting enzyme and its role in the metabolism of angiotensin I by endothelium
P Bünning, W Budek, R Escher… - Journal of …, 1986 - journals.lww.com
Angiotensin converting enzyme (ACE) was isolated from rabbit lung tissue by affinity
chromatography on an N-(l-carboxy-5-aminopentyl)-L-alanylglycine resin. The molecular …
chromatography on an N-(l-carboxy-5-aminopentyl)-L-alanylglycine resin. The molecular …
Role of angiotensin II generated by angiotensin converting enzyme-independent pathways in canine kidney.
M Murakami, H Matsuda, E Kubota… - Kidney International …, 1997 - search.ebscohost.com
Recent studies have provided evidence of angiotensin converting enzyme (ACE)-
independent angiotensin (Ang) II formation in tissue renin-angiotensin systems. We studied …
independent angiotensin (Ang) II formation in tissue renin-angiotensin systems. We studied …
Different distribution of two types of angiotensin II-generating enzymes in the aortic wall
H Okunishi, M Miyazaki, T Okamura, N Toda - Biochemical and biophysical …, 1987 - Elsevier
Dog, monkey and human aortic tissues contained two distinct types of angiotesin II-
generating enzymes; angiotensin converting enzyme (ACE) and chymostatin-sensitive …
generating enzymes; angiotensin converting enzyme (ACE) and chymostatin-sensitive …
Direct evidence for the presence of a different converting enzyme in the hamster cheek pouch.
KG Cornish, WL Joyner, JP Gilmore - Circulation Research, 1979 - Am Heart Assoc
Kininase II (angiotensin I-converting enzyme) is generally accepted to be the enzyme
responsible for the conversion of angiotensin I (AI) to angiotensin II (A II). This study …
responsible for the conversion of angiotensin I (AI) to angiotensin II (A II). This study …
Angiotensin converting enzyme activity is present in the endothelium‐denuded aorta
E Pipili, VG Manolopoulos, JD Catravas… - British journal of …, 1989 - Wiley Online Library
Angiotensin converting enzyme activity was measured in intact aortic rings utilizing the
synthetic tripeptide [3H]‐benzoyl‐Phe‐Ala‐Pro as the substrate. Intact aortic rings …
synthetic tripeptide [3H]‐benzoyl‐Phe‐Ala‐Pro as the substrate. Intact aortic rings …
Degradation of angiotensin I in the endothelium and smooth muscle of the rat aorta
MK Sim - Biochemical pharmacology, 1993 - Elsevier
In homogenates of the endothelium and smooth muscle cum adventitia of the rat aorta,
exogenous angiotensin (ANG) I was found to be degraded to des-aspartate-ANG I (des-Asp …
exogenous angiotensin (ANG) I was found to be degraded to des-aspartate-ANG I (des-Asp …