Mammographic breast density as an intermediate phenotype for breast cancer

NF Boyd, JM Rommens, K Vogt, V Lee… - The lancet …, 2005 - thelancet.com
The amount of radiologically dense breast-tissue appearing on a mammogram varies
between women because of differences in the composition of breast tissue, and is referred …

Quantitative classification of mammographic densities and breast cancer risk: results from the Canadian National Breast Screening Study

NF Boyd, JW Byng, RA Jong, EK Fishell… - JNCI: Journal of the …, 1995 - academic.oup.com
Background: The radiographic appearance of the female breast varies from woman to
woman depending on the relative amounts of fat and connective and epithelial tissues …

Mammographic density: a heritable risk factor for breast cancer

NF Boyd, LJ Martin, JM Rommens, AD Paterson… - Cancer epidemiology …, 2009 - Springer
The appearance of the breast on mammography varies among women, reflecting variations
in tissue composition. Stroma and epithelium attenuate x-rays more than fat and appear light …

[HTML][HTML] Mammographic density. Potential mechanisms of breast cancer risk associated with mammographic density: hypotheses based on epidemiological evidence

LJ Martin, NF Boyd - Breast Cancer Research, 2008 - Springer
There is now extensive evidence that mammographic density is an independent risk factor
for breast cancer that is associated with large relative and attributable risks for the disease …

Studying mammographic density: implications for understanding breast cancer

C Byrne - Journal of the National Cancer Institute, 1997 - academic.oup.com
Several epidemiologic studies (1-3) have reported the magnitude of the risk associated with
increased mammographic density to be between fourfold and sixfold, exceeding that of most …

Genetic analysis of mammographic breast density in adult women: evidence of a gene effect

JS Pankow, CM Vachon, CC Kuni… - Journal of the …, 1997 - academic.oup.com
Background: The appearance of the female breast viewed by mammography varies
considerably from one individual to another because of underlying differences in the relative …

Quantitative assessment of mammographic breast density: relationship with breast cancer risk

JA Harvey, VE Bovbjerg - Radiology, 2004 - pubs.rsna.org
Increased mammographic breast density is a moderate independent risk factor for breast
cancer, with findings of published studies in which quantitative methods of assessment were …

Mammographic density and risk of breast cancer

NF Boyd - American Society of Clinical Oncology Educational …, 2013 - ascopubs.org
The radiographic appearance of the breast on mammography varies among women, and
reflects variations in breast tissue composition and the different X-ray attenuation …

Breast-tissue composition and other risk factors for breast cancer in young women: a cross-sectional study

N Boyd, L Martin, S Chavez, A Gunasekara… - The lancet …, 2009 - thelancet.com
Background Mammographic density is a heritable quantitative trait and is a strong risk factor
for breast cancer in middle-aged and older women. However, little is known about the …

[HTML][HTML] Mammographic density and the risk of breast cancer in Japanese women

C Nagata, T Matsubara, H Fujita, Y Nagao… - British journal of …, 2005 - nature.com
Using an automated method for detecting mammographic mass, the authors evaluated the
relation between quantitatively measured density and the risk of breast cancer in a case …