Intensity-modulated radiotherapy: Is xerostomia still prevalent?

MS Chambers, AS Garden, D Rosenthal… - Current oncology …, 2005 - Springer
Conformal radiation with intensity-modulated radiotherapy (IMRT) is a technique that
potentially can minimize the dose to salivary glands and thereby decrease the incidence of …

Optimisation of conformal radiation therapy by intensity modulation: cancer of the larynx and salivary gland function

MMJ Braaksma, OB Wijers, JRS de Koste… - Radiotherapy and …, 2003 - Elsevier
Purpose: Prevention of damage to critical normal tissues is of paramount importance for the
quality of life of patients irradiated for cancers in the head and neck. The purpose of this …

Submandibular gland-sparing intensity-modulated radiotherapy

WM Mendenhall, CM Mendenhall… - American Journal of …, 2014 - journals.lww.com
Xerostomia is one of the most debilitating late effects of head and neck radiotherapy (RT)
and significantly impacts quality of life. The submandibular gland (SMG) provides …

Intensity‐modulated radiation therapy in head and neck cancers: an update

N Lee, DR Puri, AI Blanco… - Head & Neck: Journal for …, 2007 - Wiley Online Library
Intensity‐modulated radiation therapy (IMRT), an advent of three‐dimensional conformal
radiotherapy (3D CRT), has excited the profession of radiation oncology more than any …

Intensity-modulated radiotherapy significantly reduces xerostomia compared with conventional radiotherapy

PM Braam, CHJ Terhaard, JM Roesink… - International Journal of …, 2006 - Elsevier
Purpose: Xerostomia is a severe complication after radiotherapy for oropharyngeal cancer,
as the salivary glands are in close proximity with the primary tumor. Intensity-modulated …

Intensity modulated radiotherapy for head and neck cancer: evidence for preserved salivary gland function

K Saarilahti, M Kouri, J Collan, T Hämäläinen… - Radiotherapy and …, 2005 - Elsevier
BACKGROUND AND PURPOSE: To investigate the salivary gland function following
intensity modulated radiotherapy (IMRT) for head and neck cancer. PATIENTS AND …

A review of the clinical evidence for intensity-modulated radiotherapy

J Staffurth - Clinical oncology, 2010 - Elsevier
AIMS: Intensity-modulated radiotherapy (IMRT) is a development of three-dimensional
conformal radiotherapy that offers improvements in dosimetry in many clinical scenarios …

[引用][C] Reducing xerostomia by IMRT: what may, and may not, be achieved

A Eisbruch - Journal of Clinical Oncology, 2007 - ascopubs.org
Permanent xerostomia is the most prevalent late consequence of irradiation (RT) of head
and neck (HN) cancer and a major cause of reduced quality of life (QOL). 1 In addition to …

A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial …

KSC Chao, JO Deasy, J Markman, J Haynie… - International Journal of …, 2001 - Elsevier
Objectives: In a prospective clinical study, we tested the hypothesis that sparing the parotid
glands may result in significant objective and subjective improvement of xerostomia in …

Sparing of the submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer

K Saarilahti, M Kouri, J Collan, A Kangasmäki… - Radiotherapy and …, 2006 - Elsevier
BACKGROUND AND PURPOSE: The submandibular glands produce most of the
unstimulated saliva output and are the key in prevention of radiation-related xerostomia. We …