Recent advances in contrast-enhanced near infrared diffuse optical imaging of diseases using indocyanine green

D Grosenick, H Wabnitz, B Ebert - Journal of Near Infrared …, 2012 - opg.optica.org
Due to its spectral and binding properties, the well-tolerated near-infrared absorbing and
fluorescent dye indocyanine green (ICG) has found various applications in diffuse optical …

Indocyanine green fluorescence in second near-infrared (NIR-II) window

Z Starosolski, R Bhavane, KB Ghaghada… - PloS one, 2017 - journals.plos.org
Indocyanine green (ICG), a FDA approved near infrared (NIR) fluorescent agent, is used in
the clinic for a variety of applications including lymphangiography, intra-operative lymph …

Cyanine dyes as contrast agents for near-infrared imaging in vivo: acute tolerance, pharmacokinetics, and fluorescence imaging

B Ebert, B Riefke, U Sukowski… - Journal of biomedical …, 2011 - spiedigitallibrary.org
We compare pharmacokinetic, tolerance, and imaging properties of two near-IR contrast
agents, indocyanine green (ICG) and 1, 1′-bis-(4-sulfobutyl) indotricarbocyanine-5, 5 …

In vivo characterization of cyanine dyes as contrast agents for near-infrared imaging

B Riefke, K Licha, W Semmler, D Nolte… - Optical and Imaging …, 1996 - spiedigitallibrary.org
In this study indotricarbocyanines were investigated in vivo as near-infrared contrast agents.
The known dye indocyanine green (ICG) has several disadvantages regarding its use in …

Near‐infrared imaging of breast cancer using optical contrast agents

A Poellinger - Journal of biophotonics, 2012 - Wiley Online Library
Breast cancer is the most common malignancy in women worldwide and the second leading
cause of cancer death. On the basis of three studies performed by our group, this article …

First experience imaging short-wave infrared fluorescence in a large animal: indocyanine green angiography of a pig brain

BK Byrd, M Marois, KM Tichauer… - … of biomedical optics, 2019 - spiedigitallibrary.org
The potential to image subsurface fluorescent contrast agents at high spatial resolution has
facilitated growing interest in short-wave infrared (SWIR) imaging for biomedical …

Fluorescence imaging analysis of distribution of indocyanine green in molecular and nanoform in tumor model

D Farrakhova, Y Maklygina, I Romanishkin… - Photodiagnosis and …, 2022 - Elsevier
Background The efficient intraoperative identification of tumors requires the development of
highly specific near-infrared (NIR) probes as contrast agents. One of the most effective dyes …

In vivo continuous‐wave optical breast imaging enhanced with Indocyanine Green

X Intes, J Ripoll, Y Chen, S Nioka, AG Yodh… - Medical …, 2003 - Wiley Online Library
We investigate the uptake of a nontargeted contrast agent by breast tumors using a
continuous wave diffuse optical tomography apparatus. The instrument operates in the near …

[HTML][HTML] Near-infrared fluorescence imaging in humans with indocyanine green: a review and update

MV Marshall, JC Rasmussen, IC Tan… - Open surgical …, 2010 - ncbi.nlm.nih.gov
Near-infrared (NIR) fluorescence imaging clinical studies have been reported in the
literature with six different devices that employ various doses of indocyanine green (ICG) as …

Hydrophilic Cyanine Dyes as Contrast Agents for Near‐infrared Tumor Imaging: Synthesis, Photophysical Properties and Spectroscopic In vivo Characterization ¶

K Licha, B Riefke, V Ntziachristos… - Photochemistry and …, 2000 - Wiley Online Library
We have synthesized a group of glucamine and gluosamine‐substituted cyanine dyes
structurally related to indocyanine green (ICG) and have characterized these compounds …