The basophil activation test for clinical management of food allergies: recent advances and future directions

D Briceno Noriega, M Teodorowicz… - Journal of Asthma …, 2021 - Taylor & Francis
The basophil activation test (BAT) is an ex vivo functional assay that measures by flow
cytometry the degree of basophil degranulation after stimulation with an allergen. In recent …

Road map for the clinical application of the basophil activation test in food allergy

AF Santos, WG Shreffler - Clinical & Experimental Allergy, 2017 - Wiley Online Library
The diagnosis of IgE‐mediated food allergy based solely on the clinical history and the
documentation of specific IgE to whole allergen extract or single allergens is often …

Basophil activation test: food challenge in a test tube or specialist research tool?

AF Santos, G Lack - Clinical and translational allergy, 2016 - Springer
Oral food challenge (OFC) is the gold-standard to diagnose food allergy; however, it is a
labour and resource-intensive procedure with the risk of causing an acute allergic reaction …

Basophil activation test in food allergy: is it ready for real-time?

T Keswani, SU Patil - Current opinion in allergy and clinical …, 2021 - journals.lww.com
Basophil activation test in food allergy: is it ready for re... : Current Opinion in Allergy and
Clinical Immunology Basophil activation test in food allergy: is it ready for real-time? : Current …

Evaluation of basophil activation in food allergy: present and future applications

WG Shreffler - Current opinion in allergy and clinical immunology, 2006 - journals.lww.com
Although in their early stages, direct basophil activation tests may prove to be useful in the
clinic. Indirect basophil activation studies are useful when applied to compare functional …

Oral immunotherapy and basophil and mast cell reactivity in food allergy

A Paranjape, M Tsai, K Mukai, RA Hoh… - Frontiers in …, 2020 - frontiersin.org
Basophil activation tests (BATs) can closely monitor, in vitro, a patient's propensity to
develop type I hypersensitivity reactions. Because of their high specificity and sensitivity …

[PDF][PDF] Basophil activation tests in food allergy

DG Ebo - Clinical & Experimental Allergy, 2009 - researchgate.net
The 'gold standard'for diagnosis of IgE-mediated food allergy remains a properly performed
double-blind, placebo-controlled food challenge (DBPCFC)[1, 2]. However, there are …

Basophil activation test has high reproducibility and is feasible in the clinical setting

H Jaumdally, M Kwok, Z Jama… - Pediatric Allergy and …, 2022 - Wiley Online Library
Background The basophil activation test (BAT) has high accuracy to diagnose peanut
allergy and can reduce the need for oral food challenges (OFC); however, so far it has not …

Basophil activation tests for the diagnosis of food allergy in children

A Ocmant, S Mulier, L Hanssens… - Clinical & …, 2009 - Wiley Online Library
Background Positive skin prick tests (SPT) for food allergens and specific IgE (sIgE) in serum
indicate sensitization but do not enable distinction between sensitized but tolerant and …

The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease

HJ Hoffmann, AF Santos, C Mayorga, A Nopp… - Allergy, 2015 - Wiley Online Library
The basophil activation test (BAT) has become a pervasive test for allergic response through
the development of flow cytometry, discovery of activation markers such as CD 63 and …