The host response to biomaterials is a critical determinant of their success or failure in tissue‐
repair applications. Macrophages are among the first responders in the host response to …

Biologic scaffold materials composed of extracellular matrix (ECM) are routinely used for a
variety of clinical applications. Despite known variations in tissue remodeling outcomes …

Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

Recently, macrophages have been characterized as having an M1 or M2 phenotype based
on receptor expression, cytokine and effector molecule production, and function. The effects …

The early macrophage response to biomaterials has been shown to be a critical and
predictive determinant of downstream outcomes. When properly prepared, bioscaffolds …

Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix are
commonly used for the repair and functional reconstruction of injured and missing tissues …

Biologic scaffolds composed of mammalian extracellular matrix (ECM) are routinely used for
the repair and reconstruction of injured or missing tissues in a variety of pre-clinical and …

Biologic scaffolds composed of extracellular matrix (ECM) are widely used to facilitate
remodeling and reconstruction of a variety of tissues in both preclinical animal studies and …

Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …