Natural killer cell-produced IFN-γ and TNF-α induce target cell cytolysis through up-regulation of ICAM-1
R Wang, JJ Jaw, NC Stutzman, Z Zou… - Journal of leukocyte …, 2012 - academic.oup.com
ABSTRACT NK cells control tumor and virus-infected cells through releasing cytotoxic
granules and proinflammatory cytokines. IFN-γ and TNF-α secretions and cytotoxicity are …
granules and proinflammatory cytokines. IFN-γ and TNF-α secretions and cytotoxicity are …
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis
Natural killer (NK) cells can detect whether cells have undergone tumour transformation or
viral infection. The discovery of specific inhibitory receptors for major histocompatibility …
viral infection. The discovery of specific inhibitory receptors for major histocompatibility …
Signaling through CD43 induces natural killer cell activation, chemokine release, and PYK-2 activation
M Nieto, JL Rodrı́guez-Fernández… - Blood, The Journal …, 1999 - ashpublications.org
Natural killer (NK) cell activation is the result of a balance between positive and negative
signals triggered by specific membrane receptors. We report here the activation of NK cells …
signals triggered by specific membrane receptors. We report here the activation of NK cells …
Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes
D Brenner, A Golks, M Becker, W Müller… - Blood, The Journal …, 2007 - ashpublications.org
Life and death of peripheral lymphocytes is strictly controlled to maintain physiologic levels
of T and B cells. Activation-induced cell death (AICD) is one mechanism to delete …
of T and B cells. Activation-induced cell death (AICD) is one mechanism to delete …
Natural-killer cells and dendritic cells:“l'union fait la force”
Several recent publications have focused on the newly described interactions between
natural-killer (NK) cells and dendritic cells (DCs). Activated NK cells induce DC maturation …
natural-killer (NK) cells and dendritic cells (DCs). Activated NK cells induce DC maturation …
[HTML][HTML] Linking inflammation to natural killer T cell activation
M Salio, V Cerundolo - PLoS biology, 2009 - journals.plos.org
Immune activation is often associated with inflammation, but inflammation's role in the
expansion of antigen-specific immune responses remains unclear. This primer focuses on …
expansion of antigen-specific immune responses remains unclear. This primer focuses on …
Signal transduction during activation and inhibition of natural killer cells
Natural killer (NK) cells are important for early immune responses to viral infections and
cancer. Upon activation, NK cells secrete cytokines and chemokines, and kill sensitive target …
cancer. Upon activation, NK cells secrete cytokines and chemokines, and kill sensitive target …
Studies on the mechanism of human natural killer cell-mediated cytolysis: I. Modulation by dexamethasone and arachidonic acid
R Bray, S Abrams, Z Brahmi - Cellular Immunology, 1983 - Elsevier
Natural killer (NK) cell-mediated cytotoxicity, as measured by the lysis of the human
erythroleukemic cell line K562, is inhibited by the glucocorticosteroid dexamethasone …
erythroleukemic cell line K562, is inhibited by the glucocorticosteroid dexamethasone …
Cytolysis of human dendritic cells by autologous lymphokine‐activated killer cells: participation of both T cells and NK cells in the killing
P Parajuli, Y Nishioka, N Nishimura… - Journal of leukocyte …, 1999 - Wiley Online Library
Dendritic cells (DC) play a key role in the initiation of immune response by stimulating the
naive T cells. The fate of DC after the initiation of immune response is not clearly …
naive T cells. The fate of DC after the initiation of immune response is not clearly …
[HTML][HTML] Direct interaction of the CD38 cytoplasmic tail and the Lck SH2 domain: Cd38 transduces T cell activation signals through associated Lck
CD38 ligation has been shown to induce activation of intracellular signaling cascade in T
lymphocytes through a Lck-dependent pathway. However, it is not clear how Lck initiates the …
lymphocytes through a Lck-dependent pathway. However, it is not clear how Lck initiates the …