ABSTRACT NK cells control tumor and virus-infected cells through releasing cytotoxic
granules and proinflammatory cytokines. IFN-γ and TNF-α secretions and cytotoxicity are …

Natural killer (NK) cells can detect whether cells have undergone tumour transformation or
viral infection. The discovery of specific inhibitory receptors for major histocompatibility …

Natural killer (NK) cell activation is the result of a balance between positive and negative
signals triggered by specific membrane receptors. We report here the activation of NK cells …

Life and death of peripheral lymphocytes is strictly controlled to maintain physiologic levels
of T and B cells. Activation-induced cell death (AICD) is one mechanism to delete …

Several recent publications have focused on the newly described interactions between
natural-killer (NK) cells and dendritic cells (DCs). Activated NK cells induce DC maturation …

Immune activation is often associated with inflammation, but inflammation's role in the
expansion of antigen-specific immune responses remains unclear. This primer focuses on …

Natural killer (NK) cells are important for early immune responses to viral infections and
cancer. Upon activation, NK cells secrete cytokines and chemokines, and kill sensitive target …

Natural killer (NK) cell-mediated cytotoxicity, as measured by the lysis of the human
erythroleukemic cell line K562, is inhibited by the glucocorticosteroid dexamethasone …

Dendritic cells (DC) play a key role in the initiation of immune response by stimulating the
naive T cells. The fate of DC after the initiation of immune response is not clearly …

CD38 ligation has been shown to induce activation of intracellular signaling cascade in T
lymphocytes through a Lck-dependent pathway. However, it is not clear how Lck initiates the …