Evidence for galanin receptors in primary sensory neurones and effect of axotomy and inflammation

ZQ Xu, TJ Shi, M Landry, T Hökfelt - Neuroreport, 1996 - journals.lww.com
USING in situ hybridization, mRNA coding for the galanin R1 receptor (GAL-R1) was
demonstrated in> 20% of all lumbar 4 and 5 dorsal root ganglion neurone profiles, mainly …

Expression and regulation of galanin-R2 receptors in rat primary sensory neurons: effect of axotomy and inflammation

TJS Shi, X Zhang, K Holmberg, ZQD Xu, T Hökfelt - Neuroscience letters, 1997 - Elsevier
Using in situ hybridization, we studied galanin-R2 receptor (GAL-R2-R) mRNA in rat lumbar
5 dorsal root ganglia (DRGs) at different time points after peripheral tissue inflammation and …

Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behaviour

TJS Shi, X Hua, X Lu, S Malkmus… - European Journal of …, 2006 - Wiley Online Library
Galanin is a 29‐amino‐acid peptide expressed in dorsal root ganglion (DRG) neurones and
spinal dorsal horn neurones. It affects pain threshold and has developmental and trophic …

Regulation of expression of galanin and galanin receptors in dorsal root ganglia and spinal cord after axotomy and inflammation.

XU Zhang, ZO Xu, TJ Shi, M Landry… - Annals of the New …, 1998 - europepmc.org
Galanin can normally be detected only in a few dorsal root ganglion (DRG) neurons, but it is
dramatically upregulated after peripheral nerve injury in both rat and monkey. Galanin is …

Expression of the novel galanin receptor subtype GALR2 in the adult rat CNS: distinct distribution from GALR1

D O'Donnell, S Ahmad, C Wahlestedt… - Journal of …, 1999 - Wiley Online Library
Recent molecular cloning studies by our laboratory and others have identified the existence
of a novel rat galanin receptor subtype, GALR2. In the present study, we examined the …

Differential distribution and regulation of galanin receptors-1 and-2 in the rat lumbar spinal cord

P Brumovsky, F Mennicken, D O'donnell, T Hökfelt - Brain research, 2006 - Elsevier
The expression of the galanin receptor-1 and-2 (Gal1 and Gal2) messenger ribonucleic
acids (mRNAs) was studied in the lower spinal cord of rat by means of in situ hybridization …

Phenotyping of sensory and sympathetic ganglion neurons of a galanin-overexpressing mouse—possible implications for pain processing

P Brumovsky, K Hygge-Blakeman, MJ Villar… - Journal of Chemical …, 2006 - Elsevier
The distribution of galanin was studied in the lumbar 5 dorsal root ganglia (DRGs) and
spinal cord, superior cervical ganglia (SCGs), and skin of transgenic mice overexpressing …

Galanin expression in adult human dorsal root ganglion neurons: initial observations

M Landry, K Åman, J Dostrovsky, AM Lozano… - Neuroscience, 2003 - Elsevier
Human dorsal root ganglia (DRGs) were obtained during various procedures and processed
for single and double in situ hybridisation using oligonucleotide probes complementary to …

Galanin increases membrane excitability and enhances Ca2+ currents in adult, acutely dissociated dorsal root ganglion neurons

N Kerekes, F Mennicken, D O'Donnell… - European Journal of …, 2003 - Wiley Online Library
We examined the effect of galanin (10− 15–10− 7 m) on dispersed, mainly small‐sized
dorsal root ganglion (DRG) neurons in adult rats using whole‐cell patch‐clamp. Galanin and …

Galanin in Somatosensory Function a

Z WIESENFELD‐HALLIN… - Annals of the New York …, 1998 - Wiley Online Library
Galanin‐like immunoreactivity and galanin receptors are found in dorsal root ganglion
(DRG) cells and in dorsal horn interneurons, suggesting that this neuropeptide may have a …