[HTML][HTML] Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case–control study

EV Arkema, BL Goldstein, W Robinson… - Arthritis research & …, 2013 - Springer
Introduction The aim of this study was to characterize anti-citrullinated peptide antibody
(ACPA) serostatus in pre-clinical rheumatoid arthritis (RA) with and without Human …

Effects of smoking and shared epitope on the production of anti–citrullinated peptide antibody in a Japanese adult population

C Terao, K Ohmura, K Ikari, T Kawaguchi… - Arthritis care & …, 2014 - Wiley Online Library
Objective Anti–citrullinated peptide antibody (ACPA) and rheumatoid factor (RF) are markers
to rheumatoid arthritis (RA). Smoking and shared epitope (SE) in HLA–DRB1 are associated …

Arthritis development in patients with arthralgia is strongly associated with anti-citrullinated protein antibody status: a prospective cohort study

WH Bos, GJ Wolbink, M Boers, GJ Tijhuis… - Annals of the …, 2010 - ard.bmj.com
Background Anti-citrullinated protein antibodies (ACPA) are associated with increased risk
for rheumatoid arthritis. Objective To investigate the effect of the presence and levels of …

Very high levels of anti–citrullinated protein antibodies are associated with HLA–DRB1* 15 non–shared epitope allele in patients with rheumatoid arthritis

J Laki, E Lundström, O Snir, J Rönnelid… - Arthritis & …, 2012 - Wiley Online Library
Objective Production of anti–citrullinated protein antibodies (ACPAs) is an important
biomarker for rheumatoid arthritis (RA). We undertook this study to determine whether …

Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis

P Szodoray, Z Szabó, A Kapitány, Á Gyetvai… - Autoimmunity …, 2010 - Elsevier
Anti-citrullinated protein/peptide antibodies (ACPA) have recently emerged as sensitive and
specific serological markers of rheumatoid arthritis (RA), providing superior alternative of the …

Development of the anti–citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis

LA van de Stadt, MHMT de Koning… - Arthritis & …, 2011 - Wiley Online Library
Objective To examine how anti–citrullinated protein antibody (ACPA) epitope spreading
takes place prior to the onset of clinical rheumatoid arthritis (RA), and to analyze the pattern …

Autoantibodies are major predictors of arthritis development in patients with anti-citrullinated protein antibodies and musculoskeletal pain

E Eloff, K Martinsson, M Ziegelasch… - Scandinavian journal …, 2021 - Taylor & Francis
Objectives: Predictors of arthritis development are highly warranted among patients with anti-
citrullinated protein antibodies (ACPAs) and musculoskeletal symptoms to optimize clinical …

[HTML][HTML] Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis

A Zaccardelli, X Liu, JA Ford, J Cui, B Lu… - Arthritis Research & …, 2019 - Springer
Background Anti-citrullinated protein antibodies (ACPA) are central to rheumatoid arthritis
(RA) pathogenesis and may develop at inflamed mucosa. We investigated whether asthma …

[HTML][HTML] Levels of anti-citrullinated protein antibodies and IgM rheumatoid factor are not associated with outcome in early arthritis patients: a cohort study

J Ursum, WH Bos, N van Dillen, BAC Dijkmans… - Arthritis research & …, 2010 - Springer
Introduction To investigate whether baseline levels of anti-citrullinated protein antibody
(ACPA) or IgM rheumatoid factor (IgM-RF) and changes in the year thereafter are associated …

Relatives without rheumatoid arthritis show reactivity to anti–citrullinated protein/peptide antibodies that are associated with arthritis‐related traits: studies of the …

KA Young, KD Deane, LA Derber… - Arthritis & …, 2013 - Wiley Online Library
Objective To examine reactivity to anti–citrullinated protein/peptide antibodies (ACPAs) and
determine associations between ACPAs and other rheumatoid arthritis (RA)–related …