Human beta-defensin-2 (hBD-2), a small cationic peptide, exhibits a broad range of
antimicrobial activity. It has been found to play important roles in innate and adaptive …

Background Human β-defensin-3 (HBD 3) is an epithelial peptide that has been
demonstrated to have a salt-insensitive broad spectrum of potent antimicrobial activity …

The growing public health problem of infections caused by multiresistant Gram-positive
bacteria, in particularStaphylococcus aureus, prompted us to screen human epithelia for …

Human β-defensin 2 (hBD-2) is a 41-amino acid cationic peptide of the innate immune
system that serves as antimicrobial molecule. We determined the bactericidal activity of …

ABSTRACT β‐Defensins are antibiotic peptides involved in host defense at the epithelial
surface. Three human β‐defensins (hBDs)‐‐hBD‐1, hBD‐2, and hBD‐3‐‐have been …

In this work, taking human β‐defensin‐2 (HBD2) as a demonstrative molecule, the strategies
for high efficient production of functional human β‐defensins in E. coli were studied. Fusion …

Antimicrobial peptides are small, cationic, amphiphilic peptides of 12–50 amino acids with
microbicidal activity against both bacteria and fungi. The eukaryotic antimicrobial peptides …

ABSTRACT Human β-defensin 3 (hBD3) is a highly basic 45-amino-acid protein that acts
both as an antimicrobial agent and as a chemoattractant molecule. Although the nature of its …

Human β-defensin 2 (HBD2) has been shown to interact with pathogenic bacteria and
components of the mammalian innate and adaptive immune response. We describe a quick …

Abstract β-Defensins are cationic peptides produced by epithelial cells that have been
proposed to be an important component of immune function at mucosal surfaces. Similarities …