Familial amyotrophic lateral sclerosis (ALS) accounts for 10% of all ALS cases; 12–23% are
associated with mutations in the Cu/Zn superoxide dismutase gene (SOD1). All ALS-linked …

Familial amyotrophic lateral sclerosis (ALS) accounts for 10% of all ALS cases;
approximately 25% are due to mutations in the Cu/Zn superoxide dismutase gene (SOD1) …

Familial amyotrophic lateral sclerosis (ALS) accounts for 10% of all ALS. Approximately 20%
of cases are due to mutations in the Cu/Zn superoxide dismutase gene (SOD1). In North …

INTRODUCTION: Details of the mutations in the Cu/Zn superoxide dismutase (SOD1) gene
in patients with the familial form of amyotrophic lateral sclerosis are currently being gathered …

Mutations of the SOD1 gene, which encodes the enzyme copper/zinc superoxide dismutase,
are associated with familial amyotrophic lateral sclerosis (ALS). SOD1 consists of five exons …

Abstract Mutations of Cu-Zn superoxide dismutase (SOD1) have rarely been identified in
Chinese patients with amyotrophic lateral sclerosis (ALS). We recently initiated a program to …

We report different clinical expression in seven members of a large family with amyotrophic
lateral sclerosis (ALS) and the G93D mutation in exon 4 of the Cu/Zn superoxide dismutase …

Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease which
targets motor neurons of the cortex, brainstem and spinal cord. About 5–10% of all …

Amyotrophic lateral sclerosis (ALS), the most common adult onset motor neuron disease, is
pathologically characterized by progressive loss of the upper and lower motor neurons …

Mutations in the copper zinc superoxide dismutase 1 (SOD1) gene are the second most
frequent cause of familial amyotrophic lateral sclerosis (ALS). Nearly 200 mutations of this …