Wnt/β‐catenin is an evolutionarily conserved, developmental signalling pathway that
regulates embryogenesis, injury repair and pathogenesis of human diseases. Dysregulated …

Wnt/β-catenin signaling is an evolutionarily conserved, highly complex, key developmental
pathway that regulates cell fate, organ development, tissue homeostasis, as well as injury …

The Wnt/β-catenin signaling pathway plays important roles in embryonic development and
tissue homeostasis. Wnt signaling is induced, and β-catenin is activated, associated with the …

Wnt signal cascade is an evolutionarily conserved, developmental pathway that regulates
embryogenesis, injury repair, and pathogenesis of human diseases. It is well established …

Fibrosis of epithelial parenchymal organs and end-stage organ failure, the final common
pathway of many progressive chronic diseases including chronic kidney disease, continue …

Wnts compose a family of signaling proteins that play an essential role in kidney
development, but their expression in adult kidney is thought to be silenced. Here, we …

The WNT–β-catenin system is an evolutionary conserved signalling pathway that is of
particular importance for morphogenesis and cell organization during embryogenesis. The …

Activation of β-catenin, the principal mediator of canonical Wnt signaling, is a common
pathologic finding in a wide variety of chronic kidney diseases (CKD). While β-catenin is …

Wnt signalling is a complex, highly conserved, cell‐to‐cell communication pathway in
multicellular organisms, regulating cell fate, function and phenotype in development, and …

Abstract β-Catenin functions as a transducer of Wnt signals to the nucleus, where it interacts
with the T cell factor (TCF) family of DNA binding proteins to regulate gene expression. On …