Characterization of lower urinary tract dysfunction after thoracic spinal cord injury in Yucatan Minipigs

MS Keung, F Streijger, A Herrity, J Ethridge… - Journal of …, 2021 - liebertpub.com
There is an increasing need to develop approaches that will not only improve the clinical
management of neurogenic lower urinary tract dysfunction (NLUTD) after spinal cord injury …

Assessment of lower urinary tract functional deficit in rats with contusive spinal cord injury

V PIKOV, RA GILLIS, LUC JASMIN… - Journal of …, 1998 - liebertpub.com
Traumatic spinal cord injury (SCI) produces lower urinary tract (LUT) dysfunction that has
been studied in surgical transection models. Our aim was to assess LUT functional deficit in …

[HTML][HTML] Assessing Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury: Animal Models in Preclinical Neuro-Urology Research

AW Doelman, F Streijger, SJA Majerus, MS Damaser… - Biomedicines, 2023 - mdpi.com
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

Effect of injury severity on lower urinary tract function after experimental spinal cord injury

JR Wrathall, GS Emch - Progress in brain research, 2006 - Elsevier
Lower urinary tract dysfunction is a serious burden for patients following spinal cord injury.
Patients are usually limited to treatment with urinary drainage catheters, which can lead to …

Deficits in bladder function following spinal cord injury vary depending on the level of the injury

BT David, O Steward - Experimental neurology, 2010 - Elsevier
Loss of bladder function is an important consequence of a spinal cord injury (SCI) but is
rarely assessed in animal studies of SCI. Here, we use a simple outcome measure (volume …

[HTML][HTML] Lower urinary tract function in spinal cord-injured rats: midthoracic contusion versus transection

T Mitsui, M Murray, K Nonomura - Spinal Cord, 2014 - nature.com
Objectives: To compare changes in lower urinary tract (LUT) function with modifications in
pathways that regulate LUT function using two different animal models (incomplete and …

Comparison of the effects of complete and incomplete spinal cord injury on lower urinary tract function as evaluated in unanesthetized rats

PY Leung, CS Johnson, JR Wrathall - Experimental neurology, 2007 - Elsevier
In rats, phasic external urethral sphincter (EUS) activity (bursting) is postulated to be crucial
for efficient voiding. This has been reported to be lost after spinal cord transection (txSCI) …

Urological sequelae to acute spinal cord injury in pet dogs: a natural disease model of neuropathic bladder dysfunction

L Cook, J Byron, S Moore - Topics in Spinal Cord Injury …, 2019 - meridian.allenpress.com
The authors review urologic dysfunction, including urine retention, incontinence, and
recurrent and resistant urinary tract infection, in dogs as a sequela to acute spinal cord …

A noninvasive ultrasonographic method to evaluate bladder function recovery in spinal cord injured rats

HS Keirstead, V Fedulov, F Cloutier, O Steward… - Experimental …, 2005 - Elsevier
Suprasacral spinal cord injury induces changes in the mechanical and neuronal properties
of the bladder resulting in bladder areflexia followed by bladder–sphincter dyssynergia and …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …