A rodent lumbosacral spinal cord injury model reflecting neurological and urological deficits of humans

B Afrashteh, K Roider, S Bauer… - Journal of …, 2022 - scientificarchives.com
Spinal cord injury (SCI) to the terminal segments of the spinal cord causes severe disruption
of the neural circuitry of the bladder, resulting in neurogenic underactive bladder (nUAB) …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

[PDF][PDF] Identification of lower urinary tract dysfunction after spinal cord injury at lumbosacral level by developing a clinical relevance rat model

B Afrashteh - PhD diss., University of Salzburg, 2023 - eplus.uni-salzburg.at
Bladder dysfunction after lumbosacral spinal cord injury (neurogenic bladder dysfunction) is
relatively common in patients with injury. There are very few studies on this disorder, which …

Acute and chronic deficits in the urinary bladder after spinal contusion injury in the adult rat

JJ Herrera, RJL Haywood-Watson… - Journal of neurotrauma, 2010 - liebertpub.com
Traumatic spinal cord injury (SCI) permanently alters bladder function in humans. Hematuria
and cystitis occur in both human SCI as well as in rodent models of SCI. Others have …

Post‐injury bladder management strategy influences lower urinary tract dysfunction in the mouse model of spinal cord injury

N Wada, T Shimizu, S Takai, N Shimizu… - Neurourology and …, 2017 - Wiley Online Library
Aims To examine the effects of a different number of daily bladder squeezes on bladder
dysfunction in mice with spinal cord injury (SCI). Methods Spinal cord was transected at the …

Functional deficits and morphological changes in the neurogenic bladder match the severity of spinal cord compression

O Ozsoy, U Ozsoy, G Stein, O Semler… - Restorative …, 2012 - content.iospress.com
Following spinal cord injury (SCI), loss of spinal and supraspinal control results in
desynchronisation of detrusor vesicae (parasympathicus) and external urethral sphincter …

The role of spinal cord tractography in detecting lesions following selective bladder afferent and efferent fibers injury: A novel method for induction of neurogenic lower …

S Sadeghmousavi… - Neurourology and …, 2022 - Wiley Online Library
Objective Neurogenic lower urinary tract dysfunction (NLUTD), a challenging disorder, is
defined by lack of bladder control due to the abnormalities in neural pathways and can be …

Persistent polyuria in a rat spinal contusion model

PJ Ward, CH Hubscher - Journal of neurotrauma, 2012 - liebertpub.com
Polyuria contributes to bladder overdistention, which confounds both lower and upper
urinary tract management in individuals having a spinal cord injury (SCI). Bladder …

Changes in micturition after spinal cord injury in conscious rats

M Yoshiyama, FM Nezu, O Yokoyama, WC de Groat… - Urology, 1999 - Elsevier
Objectives. To determine the feasibility of urodynamic monitoring of voiding function in
conscious, female spinal cord-injured (SCI) rats and to compare the voiding function in SCI …