Invasive aspergillosis is initiated when Aspergillus fumigatus adheres to and invades the
pulmonary epithelial cells that line the airways and alveoli. To gain deeper insight into how …

Aspergillus fumigatus is an opportunistic, ubiquitous, saprophytic mould that can cause
severe allergic responses in atopic individuals as well as life-threatening infections in …

Heterogeneity among Aspergillus fumigatus isolates results in unique virulence potential
and inflammatory responses. How these isolates drive specific immune responses and how …

Aspergillus fumigatus isolates display significant heterogeneity in growth, virulence,
pathology, and inflammatory potential in multiple murine models of invasive aspergillosis …

Aspergillus fumigatus is a mold that causes severe pulmonary infections. Our knowledge of
how A. fumigatus growth is controlled in the respiratory tract is developing, but still limited …

The human lung is constantly exposed to Aspergillus fumigatus spores, the most prevalent
worldwide cause of fungal respiratory disease. Pulmonary tissue damage is a unifying …

Background Aspergillus fumigatus is the main causative agent of aspergillosis. Infections
rarely occur in immunocompetent individuals, indicating efficient clearance of conidia by …

In medically important fungi, regulatory elements that control development and asexual
reproduction often govern the expression of virulence traits. We therefore cloned the …

During the initiation of invasive aspergillosis, inhaled Aspergillus fumigatus conidia are
deposited on the epithelial cells lining the bronchi, terminal bronchioles, and alveoli. While …

Background Given the complex nature of the responses that can occur in host-pathogen
interactions, dual transcriptomics offers a powerful method of elucidating these interactions …