Abstract The key intermediate 3-aminopyrazolo [4, 3-c] pyridine-4, 6-dione (2) is considered
as a precursor for some novel pyrazolo [4, 3-c] pyridines 4a-c, arylhydrazopyrazolo [4, 3-c] …

New series of sulfonamide derivatives of [1, 3, 4] thiadiazolo [3, 2-a] pyrimidine were
synthesized and investigated as antitumor agents. Some of the newly prepared compounds …

In this study, a series of novel substituted pyrazolo [3, 4-c] pyridin-5-ylamidines was
synthesized and their cytotoxicity against three cancer cell lines (MDA-MB-231, HT-1080 …

A series of novel N-anilino-5-methyl-2-(3-(5-(alkylaminomethyl) furan-2-yl-methylthio)
propyl)-[1, 2, 4] triazolo-[1, 5-a] pyrimidine-7-amine derivatives were synthesized and …

A novel class of 5‐amino‐N′‐(1‐(pyridin‐4‐yl) ethylidene)‐1H‐pyrazole‐4‐
carbohydrazides and 8‐(pyridin‐4‐yl) pyrido [2, 3‐d][1, 2, 4] triazolo [4, 3‐a] pyrimidin‐5 (1H) …

Problem statement: This study describes the synthesis and anticancer activities of a new
series of thiazolo [3, 2-a] pyrimidines derivatives (2-7) using 3, 5-bisarylmethylene-1-methyl …

Amino-4, 6-dimethylpyrazolopyridine was applied as a precursor for the synthesis of some
new pyridopyrazolo-triazine and pyridopyrazolo-triazole derivatives through diazotization …

A series of pyrazolo [3, 4-d] pyrimidine and urea hybrids have been designed, synthesized
and evaluated for their anticancer activity in vitro and in vivo cancer models. Among them …

A novel series of thiazolo [2, 3-b] quinazoline (16–19, 25–28, and 34–37) and cyclohepta [d]
thiazolo [3, 2-a] pyrimidine (20–23, 29–32, and 38–41) analogs was designed and …

A series of novel alkyl amide functionalized trifluoromethyl substituted pyrazolo [3, 4-b]
pyridine derivatives 5, 6 and 7 were prepared starting from 6-phenyl-4-(trifluoromethyl)-1H …