Resveratrol induces acute endothelium-dependent renal vasodilation mediated through nitric oxide and reactive oxygen species scavenging

KL Gordish, WH Beierwaltes - American Journal of …, 2014 - journals.physiology.org
Resveratrol is suggested to have beneficial cardiovascular and renoprotective effects.
Resveratrol increases endothelial nitric oxide synthase (eNOS) expression and nitric oxide …

Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats

SR Bhatt, MF Lokhandwala, AA Banday - European journal of …, 2011 - Elsevier
Endothelial dysfunction is a hallmark of hypertension and vascular oxidative stress can
contribute to endothelial dysfunction and hypertension development. Resveratrol is an …

Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys

L Giovannini, M Migliori, BM Longoni… - Journal of …, 2001 - journals.lww.com
Reactive oxygen species have been implicated in the pathophysiology of renal ischemia
reperfusion injury. Antioxidants including polyphenolics have been found to protect renal …

[HTML][HTML] Resveratrol plays important role in protective mechanisms in renal disease-mini-review

G Albertoni, N Schor - Brazilian Journal of Nephrology, 2015 - SciELO Brasil
Resveratrol (RESV) is a polyphenolic compound found in various plants, including grapes,
berries and peanuts, and its processed foods as red wine. RESV possesses a variety of …

Resveratrol: A Multifunctional Compound Improving Endothelial Function: Editorial to:“Resveratrol Supplementation Gender Independently Improves Endothelial …

H Li, U Förstermann - Cardiovascular drugs and therapy, 2009 - Springer
The red wine polyphenol resveratrol boosts endothelium-dependent and-independent
vasorelaxations. The improvement of endothelial function by resveratrol is largely …

Protective effect of nitric oxide pathway in resveratrol renal ischemia-reperfusion injury in rats

V Chander, K Chopra - Archives of medical research, 2006 - Elsevier
BACKGROUND: Nitric oxide (NO), synthesized from L-arginine by the enzyme nitric oxide
synthase (NOS), seems to play an ambiguous role during tissue ischemia-reperfusion (I/R) …

[HTML][HTML] Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury

JH Holthoff, Z Wang, KA Seely, N Gokden… - Kidney international, 2012 - Elsevier
The mortality rate of patients who develop acute kidney injury during sepsis nearly doubles.
The effectiveness of therapy is hampered because it is usually initiated only after the onset …

Resveratrol lowers blood pressure in spontaneously hypertensive rats via calcium-dependent endothelial NO production

X Li, Y Dai, S Yan, Y Shi, J Li, J Liu… - Clinical and …, 2016 - Taylor & Francis
Objective: Resveratrol, a polyphenol of natural compounds, has beneficial cardiovascular
effects, many of which are mediated by nitric oxide (NO). Resveratrol increases intracellular …

Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats

AA Javkhedkar, Y Quiroz… - American Journal …, 2015 - journals.physiology.org
Compelling evidence supports the role of oxidative stress and renal interstitial inflammation
in the pathogenesis of hypertension. Resveratrol is a polyphenolic stilbene, which can lower …

[HTML][HTML] Resveratrol improved kidney function and structure in malignantly hypertensive rats by restoration of antioxidant capacity and nitric oxide bioavailability

J Grujić-Milanović, V Jaćević, Z Miloradović… - Biomedicine & …, 2022 - Elsevier
Objective Background The main cause of death among patients with malignant hypertension
is a kidney failure. The promising field in essential and malignant hypertension therapy …