Recent work has implicated dopaminergic mechanisms in overeating and obesity with some
researchers suggesting parallels between the dopamine dysregulation associated with …

The hypothalamus integrates various hormonal and neuronal signals to regulate appetite
and metabolism and thereby serves a homeostatic purpose in the regulation of body weight …

Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …

Increased caloric intake in dietary obesity could be driven by central mechanisms that
regulate reward-seeking behavior. The mesolimbic dopamine system, and the nucleus …

Abstract Purpose of Review Animal and human studies suggest that diet-induced obesity
and plasticity in the central dopaminergic system are linked. However, it is unclear whether …

Accumulating evidence indicates integration of dopamine function with metabolic signals,
highlighting a potential role for dopamine in energy balance, frequently construed as …

There is increasing evidence demonstrating that reward-related motivational food intake is
closely connected with the brain's homeostatic system of energy balance and that this …

The role of the dopamine D2 receptor (D2R) in regulating appetitive behavior continues to
be controversial. Earlier literature suggests that reduced D2R signaling diminishes …

The increasing worldwide prevalence of obesity is partially related to the ready availability of
highly palatable foods which increases the incidence of hedonic, non-homeostatic feeding …

The association between dietary obesity and mesolimbic systems that regulate hedonic
aspects of feeding is currently unresolved. In the present study, we examined differences in …