Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures

ME Brown, RS El-Mallakh - Therapeutics and clinical risk …, 2010 - Taylor & Francis
Eslicarbazepine is a new dibenzazepine antiepileptic agent. It is a high affinity antagonist of
the voltage-gated sodium channel. It is closely related to both carbamazepine and …

A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures

R Rocamora - Therapeutic advances in neurological …, 2015 - journals.sagepub.com
Eslicarbazepine acetate is a is a once-daily antiepileptic drug (AED) that was approved in
2009 by the European Medicines Agency (EMA)(Zebinix™), and in 2013 by the US Food …

Eslicarbazepine acetate as adjunctive therapy in adult patients with partial epilepsy

E Ben-Menachem, AA Gabbai, A Hufnagel, J Maia… - Epilepsy research, 2010 - Elsevier
OBJECTIVE: To investigate the efficacy and safety of once-daily eslicarbazepine acetate
(ESL) when used as add-on treatment in adults with≥ 4 partial-onset seizures per 4-week …

Efficacy and safety of 800 and 1200 mg eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures

A Gil‐Nagel, J Lopes‐Lima, L Almeida… - Acta Neurologica …, 2009 - Wiley Online Library
Objectives–To evaluate the efficacy and safety of eslicarbazepine acetate (ESL) as
adjunctive therapy in adults with partial‐onset seizures. Material and methods–Double …

[HTML][HTML] Eslicarbazepine acetate: a new improvement on a classic drug family for the treatment of partial-onset seizures

GL Galiana, AC Gauthier, RH Mattson - Drugs in R&D, 2017 - Springer
Eslicarbazepine acetate is a new anti-epileptic drug belonging to the dibenzazepine
carboxamide family that is currently approved as adjunctive therapy and monotherapy for …

Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial‐onset seizures: a randomized, double‐blind, placebo‐controlled …

C Elger, P Halász, J Maia, L Almeida… - …, 2009 - Wiley Online Library
Purpose: To study the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive
therapy for refractory partial seizures in adults with≥ 4 partial‐onset seizures (simple or …

Eslicarbazepine acetate: an update on efficacy and safety in epilepsy

A Verrotti, G Loiacono, A Rossi, G Zaccara - Epilepsy research, 2014 - Elsevier
Epilepsy is a common neurological disorder. Despite a broad range of commonly used
antiepileptic drugs, approximately 30% of patients with epilepsy have drug resistance or …

Update on treatment of partial onset epilepsy: role of eslicarbazepine

M Rauchenzauner, G Luef - Neuropsychiatric disease and …, 2010 - Taylor & Francis
Partial epilepsy comprises simple partial seizures, complex partial seizures, and secondarily
generalized seizures, and covers more than 60% of patients with epilepsy. Antiepileptic …

Eslicarbazepine acetate in the treatment of adults with partial-onset epilepsy: an evidence-based review of efficacy, safety and place in therapy

S Lattanzi, F Brigo, C Cagnetti, A Verrotti… - Core …, 2018 - Taylor & Francis
Introduction: Up to 30% of the patients diagnosed with epilepsy will continue suffering from
seizures despite treatment with antiepileptic drugs, either in monotherapy or polytherapy …

Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial‐onset seizures: results of a phase III, double‐blind, randomized, placebo‐controlled …

MR Sperling, B Abou‐Khalil, J Harvey, JB Rogin… - …, 2015 - Wiley Online Library
Objective To evaluate the efficacy and safety of adjunctive eslicarbazepine acetate (ESL) in
patients with refractory partial‐onset seizures. Methods This randomized, placebo …