Deficits in discrimination after experimental frontal brain injury are mediated by motivation and can be improved by nicotinamide administration
C Vonder Haar, WR Maass, EA Jacobs… - Journal of …, 2014 - liebertpub.com
One of the largest challenges in experimental neurotrauma work is the development of
models relevant to the human condition. This includes both creating similar pathophysiology …
models relevant to the human condition. This includes both creating similar pathophysiology …
[HTML][HTML] Loss of consciousness and righting reflex following traumatic brain injury: predictors of post-injury symptom development (a narrative review)
Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …
Weight-drop model as a valuable tool to study potential neurobiological processes underlying behavioral and cognitive changes secondary to mild traumatic brain …
CA Machado, B da Silva Oliveira, TL Dias… - Journal of …, 2023 - Elsevier
The pathophysiology of post-traumatic brain injury (TBI) behavioral and cognitive changes is
not fully understood, especially in its mild presentation. We designed a weight drop TBI …
not fully understood, especially in its mild presentation. We designed a weight drop TBI …
A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats
Behavioral analysis commonly assesses cognitive deficits in rodents following traumatic
brain injury (TBI). We examined rats that received sham, mild or moderate injury in the …
brain injury (TBI). We examined rats that received sham, mild or moderate injury in the …
Minor functional deficits in basic response patterns for reinforcement after frontal traumatic brain injury in rats
C Vonder Haar, CA Winstanley - Journal of neurotrauma, 2016 - liebertpub.com
Traumatic brain injury (TBI) is a major contributor to numerous psychiatric conditions and
chronic behavioral dysfunction. Recent studies in experimental brain injury have begun to …
chronic behavioral dysfunction. Recent studies in experimental brain injury have begun to …
Evaluation of touchscreen chambers to assess cognition in adult mice: effect of training and mild traumatic brain injury
Cognitive impairments are often experienced after a mild traumatic brain injury (mTBI). In the
clinical arena, neuropsychological assessments are used frequently to detect cognitive …
clinical arena, neuropsychological assessments are used frequently to detect cognitive …
Cognitive and neuropsychiatric impairments vary as a function of injury severity at 12 months post-experimental diffuse traumatic brain injury: Implications for dementia …
Traumatic brain injury (TBI) is a common risk factor for later neurodegeneration, which can
manifest as dementia. Despite this, little is known about the time-course of development of …
manifest as dementia. Despite this, little is known about the time-course of development of …
[HTML][HTML] modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury
AD Sauerbeck, C Fanizzi, JH Kim, M Gangolli… - Scientific reports, 2018 - nature.com
Traumatic brain injury is a major source of global disability and mortality. Preclinical TBI
models are a crucial component of therapeutic investigation. We report a tunable, monitored …
models are a crucial component of therapeutic investigation. We report a tunable, monitored …
Visual dysfunction after repetitive mild traumatic brain injury in a mouse model and ramifications on behavioral metrics
NJ Morriss, GM Conley, N Hodgson… - Journal of …, 2021 - liebertpub.com
Mild traumatic brain injury (mTBI) is a major cause of morbidity and mortality with a poorly
understood pathophysiology. Animal models have been increasingly utilized to better …
understood pathophysiology. Animal models have been increasingly utilized to better …
[HTML][HTML] Translational considerations for behavioral impairment and rehabilitation strategies after diffuse traumatic brain injury
TC Thomas, TA Colburn, K Korp, A Khodadad… - 2015 - europepmc.org
Millions of diffuse traumatic brain injuries (TBI) occur annually through sports-related
incidents, motor vehicle accidents, falls and violence; many of which are never reported …
incidents, motor vehicle accidents, falls and violence; many of which are never reported …