Strong expression of FOXP1 identifies a distinct subset of diffuse large B-cell lymphoma (DLBCL) patients with poor outcome

SL Barrans, JAL Fenton, A Banham, RG Owen… - Blood, 2004 - ashpublications.org
Abstract FOXP1 (Forkhead box-P1) is a winged-helix transcription factor that is differentially
expressed in resting and activated B cells. FOXP1 expression has been demonstrated in a …

Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma

AH Banham, JM Connors, PJ Brown, JL Cordell… - Clinical cancer …, 2005 - AACR
Gene expression profiling studies have reported up-regulated mRNA expression of the
FOXP1 forkhead transcription factor in response to normal B-cell activation and high …

Potentially oncogenic B-cell activation–induced smaller isoforms of FOXP1 are highly expressed in the activated B cell–like subtype of DLBCL

PJ Brown, SL Ashe, E Leich, C Burek… - Blood, The Journal …, 2008 - ashpublications.org
The FOXP1 forkhead transcription factor is targeted by recurrent chromosome translocations
in several subtypes of B-cell non-Hodgkin lymphomas, where high-level FOXP1 protein …

The significance of FOXP1 in diffuse large B-cell lymphoma

DM Gascoyne, AH Banham - Leukemia & lymphoma, 2017 - Taylor & Francis
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of mature B-cell
lymphoma. While the majority of patients are cured with immunochemotherapy incorporating …

[HTML][HTML] Overexpression of FoxM1 offers a promising therapeutic target in diffuse large B-cell lymphoma

S Uddin, AR Hussain, M Ahmed, K Siddiqui… - …, 2012 - ncbi.nlm.nih.gov
Background FoxM1 has been shown to play a critical role in the pathogenesis of various
epithelial malignancies. However, its role in lymphoid malignancies has not been fully …

t(3;14)(p14;q32) Results in aberrant expression of FOXP1 in a case of diffuse large B‐cell lymphoma

JAL Fenton, E Schuuring, SL Barrans… - Genes …, 2006 - Wiley Online Library
Strong expression of Forkhead box‐P1 (FOXP1), a winged‐helix transcription factor, has
been identified as an independent prognostic factor in diffuse large B‐cell lymphoma …

[HTML][HTML] FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas

PJ Brown, KK Wong, SL Felce, L Lyne, H Spearman… - Leukemia, 2016 - nature.com
The FOXP1 (forkhead box P1) transcription factor is a marker of poor prognosis in diffuse
large B-cell lymphoma (DLBCL). Here microarray analysis of FOXP1-silenced DLBCL cell …

Analysis of FOXO1 mutations in diffuse large B-cell lymphoma

DL Trinh, DW Scott, RD Morin… - Blood, The Journal …, 2013 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) accounts for 30% to 40% of newly diagnosed
lymphomas and has an overall cure rate of approximately 60%. Previously, we observed …

FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations

I Wlodarska, E Veyt, P De Paepe, P Vandenberghe… - Leukemia, 2005 - nature.com
The transcription factor Forkhead box protein P1 (FOXP1) is highly expressed in a
proportion of diffuse large B-cell lymphoma (DLBCL). In this report, we provide cytogenetic …

The hematopoietic oncoprotein FOXP1 promotes tumor cell survival in diffuse large B-cell lymphoma by repressing S1PR2 signaling

M Flori, CA Schmid, ET Sumrall… - Blood, The Journal …, 2016 - ashpublications.org
Aberrant expression of the oncogenic transcription factor forkhead box protein 1 (FOXP1) is
a common feature of diffuse large B-cell lymphoma (DLBCL). We have combined chromatin …